Macrophage Pattern Recognition Receptors in Immunity, Homeostasis and Self Tolerance

被引：51

作者：

Mukhopadhyay, Subhankar ^{[1
]}

Plueddemann, Annette ^{[1
]}

Gordon, Siamon ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

TARGET PATTERN RECOGNITION IN INNATE IMMUNITY | 2009年 / 653卷

基金：

英国医学研究理事会;

关键词：

C-TYPE LECTIN; LOW-DENSITY-LIPOPROTEIN; A SCAVENGER RECEPTOR; BETA-GLUCAN RECEPTOR; CYSTEINE-RICH DOMAIN; TARGET DC-SIGN; MANNOSE RECEPTOR; DENDRITIC CELLS; INNATE IMMUNITY; MARGINAL ZONE;

D O I：

10.1109/TENCON.2009.5396176

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Macrophages, a major component of innate immune defence, express a large repertoire of different classes of pattern recognition receptors and other surface antigens which determine the immunologic and homeostatic potential of these versatile cells. In the light of present knowledge of macrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system.

引用

页码：1 / 14

页数：14

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