Diagnostic and prognostic value of biomarkers in acute myocardial infarction

被引：72

作者：

Chen, Yuqi ^{[1
]}

Tao, Yifei ^{[1
]}

Zhang, Lan ^{[1
]}

Xu, Weiting ^{[1
]}

Zhou, Xiang ^{[1
]}

机构：

[1] Soochow Univ, Affiliated Hosp 2, Dept Cardiol, Suzhou, Peoples R China

来源：

POSTGRADUATE MEDICAL JOURNAL | 2019年 / 95卷 / 1122期

基金：

中国国家自然科学基金;

关键词：

ACUTE CORONARY SYNDROME; C-REACTIVE PROTEIN; ACID-BINDING PROTEIN; GROWTH-DIFFERENTIATION FACTOR-15; CREATINE KINASE-MB; CARDIAC TROPONIN-T; TIMI RISK SCORE; NATRIURETIC PEPTIDE; CARDIOVASCULAR-DISEASE; EMERGENCY-DEPARTMENT;

D O I：

10.1136/postgradmedj-2019-136409

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incidence of acute myocardial infarction (AMI) has been increasing rapidly in recent years, seriously endangering human health. Cardiac biomarkers play critical roles in the diagnosis and prognosis of AMI. Troponin is a highly sensitive and specific biomarker for AMI diagnosis and can independently predict adverse cardiac events. Other biomarkers such as N-terminal B-type natriuretic peptide and C reactive protein are also valuable predictors of cardiovascular prognosis. Recently, several novel biomarkers have been identified for the diagnosis and risk assessment in patients with AMI. A multibiomarker approach can potentially enhance the diagnostic accuracy and provide more information for the early risk stratification of AMI. In this review, we will summarise the biomarkers discovered in recent years and focus on their diagnostic and prognostic value for patients with AMI.

引用

页码：210 / 216

页数：7

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