Theoretical Implications of a Pre-Erythrocytic Plasmodium vivax Vaccine for Preventing Relapses

被引：29

作者：

White, Michael ^{[1
,2
]}

Amino, Rogerio ^{[3
]}

Mueller, Ivo ^{[2
,3
]}

机构：

[1] Imperial Coll London, Dept Infect Dis Epidemiol, MRC Ctr Outbreak Anal & Modelling, London, England

[2] Walter & Eliza Hall Inst Med Res, Div Populat Hlth & Immun, Melbourne, Vic, Australia

[3] Inst Pasteur, Dept Parasites & Insect Vectors, Paris, France

来源：

TRENDS IN PARASITOLOGY | 2017年 / 33卷 / 04期

关键词：

MALARIA; SPOROZOITES; EFFICACY; SAFETY;

D O I：

10.1016/j.pt.2016.12.011

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses. We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.

引用

页码：260 / 263

页数：4

共 12 条

[1] A retrospective examination of reinfection of humans with Plasmodium vivax [J].

Collins, WE ;

Jeffery, GM ;

Roberts, JM .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2004, 70 (06) :642-644

[2] Randomized, Double-Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria-Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection [J].

Kester, Kent E. ;

Cummings, James F. ;

Ofori-Anyinam, Opokua ;

Ockenhouse, Christian F. ;

Krzych, Urszula ;

Moris, Philippe ;

Schwenk, Robert ;

Nielsen, Robin A. ;

Debebe, Zufan ;

Pinelis, Evgeny ;

Juompan, Laure ;

Williams, Jack ;

Dowler, Megan ;

Stewart, V. Ann ;

Wirtz, Robert A. ;

Dubois, Marie-Claude ;

Lievens, Marc ;

Cohen, Joe ;

Ballou, W. Ripley ;

Heppner, D. Gray, Jr. .

JOURNAL OF INFECTIOUS DISEASES, 2009, 200 (03) :337-346

[3] Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P-vivax Gametocytaemia in Papua New Guinea [J].

Koepfli, Cristian ;

Robinson, Leanne J. ;

Rarau, Patricia ;

Salib, Mary ;

Sambale, Naomi ;

Wampfler, Rahel ;

Betuela, Inoni ;

Nuitragool, Wang ;

Barry, Alyssa E. ;

Siba, Peter ;

Felger, Ingrid ;

Mueller, Ivo .

PLOS ONE, 2015, 10 (05)

[4] Treatment of vivax malaria on the western border of Thailand [J].

Luxemburger, C ;

van Vugt, M ;

Jonathan, S ;

McGready, R ;

Looareesuwan, S ;

White, NJ ;

Nosten, F .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1999, 93 (04) :433-438

[5]

LYSENKO AJ, 1977, B WORLD HEALTH ORGAN, V55, P541

[6] Plasmodium vivax Liver Stage Development and Hypnozoite Persistence in Human Liver-Chimeric Mice [J].

Mikolajczak, Sebastian A. ;

Vaughan, Ashley M. ;

Kangwanrangsan, Niwat ;

Roobsoong, Wanlapa ;

Fishbaugher, Matthew ;

Yimamnuaychok, Narathatai ;

Rezakhani, Nastaran ;

Lakshmanan, Viswanathan ;

Singh, Naresh ;

Kaushansky, Alexis ;

Camargo, Nelly ;

Baldwin, Michael ;

Lindner, Scott E. ;

Adams, John H. ;

Sattabongkot, Jetsumon ;

Kappe, Stefan H. I. .

CELL HOST & MICROBE, 2015, 17 (04) :526-535

[7] Development of vaccines for Plasmodium vivax malaria [J].

Mueller, Ivo ;

Shakri, Ahmad Rushdi ;

Chitnis, Chetan E. .

VACCINE, 2015, 33 (52) :7489-7495

[8] Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [J].

Robinson, Leanne J. ;

Wampfler, Rahel ;

Betuela, Inoni ;

Karl, Stephan ;

White, Michael T. ;

Suen, Connie S. N. Li Wai ;

Hofmann, Natalie E. ;

Kinboro, Benson ;

Waltmann, Andreea ;

Brewster, Jessica ;

Lorry, Lina ;

Tarongka, Nandao ;

Samol, Lornah ;

Silkey, Mariabeth ;

Bassat, Quique ;

Siba, Peter M. ;

Schofield, Louis ;

Felger, Ingrid ;

Mueller, Ivo .

PLOS MEDICINE, 2015, 12 (10)

[9] Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial [J].

Tinto, H. ;

D'Alessandro, U. ;

Sorgho, H. ;

Valea, I. ;

Tahita, M. C. ;

Kabore, W. ;

Kiemde, F. ;

Lompo, P. ;

Ouedraogo, S. ;

Derra, K. ;

Ouedraogo, F. ;

Ouedraogo, J. B. ;

Ballou, W. R. ;

Cohen, J. ;

Guerra, Y. ;

Heerwegh, D. ;

Jongert, E. ;

Lapierre, D. ;

Leach, A. ;

Lievens, M. ;

Ofori-Anyinam, O. ;

Olivier, A. ;

Vekemans, J. ;

Agnandji, S. T. ;

Lell, B. ;

Fernandes, J. F. ;

Abossolo, B. P. ;

Kabwende, A. L. ;

Adegnika, A. A. ;

Mordmueller, B. ;

Issifou, S. ;

Kremsner, P. G. ;

Loembe, M. M. ;

Bache, E. ;

Alabi, A. ;

Owusu-Agyei, S. ;

Asante, K. P. ;

Boahen, O. ;

Dosoo, D. ;

Asante, I. ;

Yidana, Z. ;

Anim, J. ;

Adeniji, E. ;

Yawson, A. K. ;

Kayan, K. ;

Chandramohan, D. ;

Greenwood, B. ;

Ansong, D. ;

Agbenyega, T. ;

Adjei, S. .

LANCET, 2015, 386 (9988) :31-45

[10] Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoes [J].

Vanderberg, JP ;

Frevert, U .

INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2004, 34 (09) :991-996

← 1 2 →