Practical guide to sample size calculations: superiority trials

被引：18

作者：

Flight, Laura ^{[1
]}

Julious, Steven A. ^{[1
]}

机构：

[1] Univ Sheffield, Med Stat Grp, Sheffield, S Yorkshire, England

来源：

PHARMACEUTICAL STATISTICS | 2016年 / 15卷 / 01期

关键词：

sample size; superiority; power; clinical trials;

D O I：

10.1002/pst.1718

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A sample size justification is a vital part of any investigation. However, estimating the number of participants required to give meaningful results is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the steps for conducting sample size calculations for superiority trials are summarised. Practical advice and examples are provided illustrating how to carry out the calculations by hand and using the app SampSize. Copyright (c) 2015 John Wiley & Sons, Ltd.

引用

页码：75 / 79

页数：5

共 5 条

[1] Practical guide to sample size calculations: non-inferiority and equivalence trials
Flight, Laura
Julious, Steven A.
[J]. PHARMACEUTICAL STATISTICS, 2016, 15 (01) : 80 - 89
[2] Practical guide to sample size calculations: an introduction
Flight, Laura
Julious, Steven A.
[J]. PHARMACEUTICAL STATISTICS, 2016, 15 (01) : 68 - 74
[3] Tutorial in biostatistics - Sample sizes for clinical trials with normal data
Julious, SA
[J]. STATISTICS IN MEDICINE, 2004, 23 (12) : 1921 - 1986
[4] Julious SA, 2009, SAMPLE SIZES FOR CLI
[5] Computer Therapy Compared With Usual Care for People With Long-Standing Aphasia Poststroke A Pilot Randomized Controlled Trial
Palmer, Rebecca
Enderby, Pam
Cooper, Cindy
Latimer, Nick
Julious, Steven
Paterson, Gail
Dimairo, Munyaradzi
Dixon, Simon
Mortley, Jane
Hilton, Rose
Delaney, Audrey
Hughes, Helen
[J]. STROKE, 2012, 43 (07) : 1904 - 1911

← 1 →