International cooperation to improve access to and sustain effectiveness of antimicrobials

被引：106

作者：

Ardal, Christine ^{[1
]}

Outterson, Kevin ^{[2
,3
]}

Hoffman, Steven J. ^{[4
,5
]}

Ghafur, Abdul ^{[6
]}

Sharland, Mike ^{[7
]}

Ranganathan, Nisha ^{[8
]}

Smith, Richard ^{[9
]}

Zorzet, Anna ^{[11
,12
]}

Cohn, Jennifer ^{[13
,14
]}

Pittet, Didier ^{[15
,16
]}

Daulaire, Nils ^{[1
]}

Morel, Chantal ^{[15
,17
]}

Rizvi, Zain ^{[18
]}

Balasegaram, Manica ^{[13
]}

Dar, Osman A. ^{[3
,19
]}

Heymann, David L. ^{[3
,10
,19
]}

Holmes, Alison H. ^{[20
,21
]}

Moore, Luke S. P. ^{[20
,21
]}

Laxminarayan, Ramanan ^{[22
,23
,24
]}

Mendelson, Marc ^{[25
]}

Rottingen, John-Arne ^{[1
,5
,26
]}

机构：

[1] Norwegian Inst Publ Hlth, N-0403 Oslo, Norway

[2] Boston Univ, Sch Law, Boston, MA 02215 USA

[3] Chatham House Ctr Global Hlth Secur, London, England

[4] Univ Ottawa, Global Strategy Lab, Fac Law, Ottawa, ON, Canada

[5] Harvard Univ, TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA 02115 USA

[6] Apollo Hosp, Madras, Tamil Nadu, India

[7] St Georges Univ, Pediat Infect Dis Res Grp, London, England

[8] Worldwide Antimalarial Resistance Network, Oxford, England

[9] Fac Publ Hlth & Policy, London, England

[10] Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England

[11] Uppsala Univ, Uppsala, Sweden

[12] ReAct Act Antibiot Resistance, Uppsala, Sweden

[13] Access Campaign, Med Sans Frontieres, Geneva, Switzerland

[14] Univ Penn, Div Infect Dis, Philadelphia, PA 19104 USA

[15] Univ Hosp Geneva, Fac Med, Geneva, Switzerland

[16] WHO Collaborating Ctr Patient Safety, Geneva, Switzerland

[17] Univ London London Sch Econ & Polit Sci, LSE Hlth, London WC2A 2AE, England

[18] Yale Univ, Sch Law, New Haven, CT 06520 USA

[19] Publ Hlth England, London, England

[20] Univ London Imperial Coll Sci Technol & Med, Natl Inst Hlth, Res Unit Healthcare Associated Infect, Res Hlth Protect, London, England

[21] Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis, London, England

[22] Ctr Dis Dynam Econ & Policy, Washington, DC USA

[23] Princeton Environm Inst, Princeton, NJ USA

[24] Publ Hlth Fdn India, New Delhi, India

[25] Univ Cape Town, Groote Schuur Hosp, Dept Med, Div Infect Dis & HIV Med, ZA-7925 Cape Town, South Africa

[26] Univ Oslo, Fac Med, Inst Hlth & Soc, Oslo, Norway

来源：

LANCET | 2016年 / 387卷 / 10015期

基金：

加拿大健康研究院;

关键词：

RESEARCH-AND-DEVELOPMENT; GLOBAL HEALTH TREATIES; MECHANISMS; AGREEMENT;

D O I：

10.1016/S0140-6736(15)00470-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Securing access to effective antimicrobials is one of the greatest challenges today. Until now, efforts to address this issue have been isolated and uncoordinated, with little focus on sustainable and international solutions. Global collective action is necessary to improve access to life-saving antimicrobials, conserving them, and ensuring continued innovation. Access, conservation, and innovation are beneficial when achieved independently, but much more effective and sustainable if implemented in concert within and across countries. WHO alone will not be able to drive these actions. It will require a multisector response (including the health, agriculture, and veterinary sectors), global coordination, and financing mechanisms with sufficient mandates, authority, resources, and power. Fortunately, securing access to effective antimicrobials has finally gained a place on the global political agenda, and we call on policy makers to develop, endorse, and finance new global institutional arrangements that can ensure robust implementation and bold collective action.

引用

页码：296 / 307

页数：12

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