Characterization of CS/PVA/GO electrospun nanofiber membrane with astaxanthin

被引：9

作者：

Zhang, Hengfang ^{[1
]}

Lin, Lexun ^{[2
]}

Ren, Liping ^{[1
]}

Liu, Yongxu ^{[3
]}

Song, Rong ^{[1
]}

机构：

[1] Harbin Med Univ, Affiliated Hosp 1, Coll Stomatol, 143 Yiman St, Harbin 150001, Peoples R China

[2] Harbin Med Univ, Sch Basic Med Sci, Dept Pathogen Microbiol, Harbin, Peoples R China

[3] Northeast Forestry Univ, Inst Mat Sci & Engn, Harbin, Peoples R China

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2021年 / 138卷 / 14期

关键词：

astaxanthin (ASTA); cytocompatibility; electrospinning; graphene oxide (GO); nanofiber membrane; GRAPHENE; BIOSYNTHESIS;

D O I：

10.1002/app.50166

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Tissue engineering has been widely used in regenerative medicine and tissue engineering scaffolds have become a new research direction for periodontal regenerative repair. We aim to develop a biological scaffold material that can support host immunity and promote periodontal regeneration. In this paper, chitosan (CS)/polyvinyl alcohol (PVA)/graphene oxide (GO)/astaxanthin (ASTA) nanofibers membranes were prepared by electrospinning. The nanofibers were characterized by scanning electron microscopy, infrared spectroscopy, mechanical testing, antibacterial testing and cytotoxicity testing. The CS/PVA/GO/ASTA nanofiber membrane had favorable micro-morphology, good mechanical properties and no cytotoxicity. This preliminary study demonstrates that the CS/PVA/GO/ASTA nanofiber membrane can be used for in vivo and in vitro experiments related to periodontal regeneration. The related mechanism of periodontal regeneration will be evaluated in future studies.

引用

页数：7

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