Chemical Constituents and Antimicrobial Activity of Branches and Leaves of Cordia insignis (Boraginaceae)

被引:5
作者
Correia, Francyne C. S. [1 ]
Targanski, Sabrina K. [1 ]
Bomfim, Tamires R. D. [1 ]
da Silva, Yasmin S. A. D. [2 ]
Violante, Ivana M. P. [2 ]
de Carvalho, Mario G. [3 ]
de Sousa Jr, Paulo T. [1 ]
Silva, Virginia C. P. [1 ]
Ribeiro, Tereza A. N. [1 ]
机构
[1] Univ Fed Mato Grosso, Dept Quim, Ave Fernando Correa da Costa 2367, BR-78060900 Cuiaba, MT, Brazil
[2] Univ Cuiaba, Ctr Pesquisa, Fac Farm Bioquim, Rua Jose de Arruda 3100, BR-78065900 Cuiaba, MT, Brazil
[3] Univ Fed Rural Rio de Janeiro, Inst Quim, BR 465,Km 07, BR-23890000 Seropedica, RJ, Brazil
关键词
Cordia insignis; secundary metabolites; antifungal activity; PLANTS; ANTIBACTERIAL; ANTIOXIDANT;
D O I
10.21577/1984-6835.20200063
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Phytochemical investigation of the branches and leaves of the species Cordia insignis led to the isolation and identification of 6-sitosterol (1), stigmasterol (2), campesterol (3),beta-sitosterol 3-O-beta-D-glucopyranoside (4), stigmasterol 3-O-beta-D-glucopyranoside (5), scoparone (6), alpha-amyrin (7), beta-amyrin (8), methyl caffeate (9), allantoin (10), scopoletin (11), caffeic acid (12), methyl rosmarinate (13). These substances had their structures determined by analysis of their 1D and 2D NMR and GC-MS spectra and by comparison with data reported in the literature. The hydroethanolic extracts of the branches and leaves and their respective fractions were submitted to antibacterial and antifungal evaluation. The extracts and fractions showed good antifungal activity but did not present antibacterial activity. This study is the first work with C. insignis.
引用
收藏
页码:809 / 816
页数:8
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