A hydrogel based fluorescent micro array used for the characterization of liquid analytes

被引:22
作者
Thete, A. R. [1 ]
Henkel, T. [2 ]
Goeckeritz, R. [1 ]
Endlich, M. [1 ]
Koehler, J. M. [1 ]
Gross, G. A. [1 ]
机构
[1] Tech Univ Ilmenau, Inst Micro & Nano Technol, Dept Phys Chem & Microreact Technol, D-98693 Ilmenau, Germany
[2] Inst Photon Technol, Dept Microfluid Devices, D-07745 Jena, Germany
关键词
Chemo chips; Sensor array; Fluorescence imaging; Pattern recognition; Analytical array; Optochemical tongue; COLORIMETRIC SENSOR ARRAYS; ELECTRONIC TONGUE; NOSE; DESIGN; FTIR; PH;
D O I
10.1016/j.aca.2008.11.030
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A fluorimetric micro spot array using non-specific recognition function is described for the analysis of liquid samples. The array was composed of binary mixtures of various fluorescence dyes which were embedded in a hydrogel matrix. The interactions between the fluorescent dyes and their molecular surrounding-inside the hydrogel. influence their fluorescence wave length and intensities. The array was used for the characterization of solvent mixtures, Developed fluorescence patterns of the complete array as well as the fluorescence intensity changes of single spots were analysed. It was proven, that specific analytical information can be gained using this non-specific recognition approach. The identification of some alcoholic beverages is described as an example of the application of this method when used for quality control Purposes. Analogous to the appellation "electronic nose" and "electronic tongue" the described micro spot array acts as an "optochemical tongue". (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:81 / 89
页数:9
相关论文
共 29 条
[1]   Polymers in sensor applications [J].
Adhikari, B ;
Majumdar, S .
PROGRESS IN POLYMER SCIENCE, 2004, 29 (07) :699-766
[2]   Cross-reactive chemical sensor arrays [J].
Albert, KJ ;
Lewis, NS ;
Schauer, CL ;
Sotzing, GA ;
Stitzel, SE ;
Vaid, TP ;
Walt, DR .
CHEMICAL REVIEWS, 2000, 100 (07) :2595-2626
[3]   A fluorescent chemosensor for Zn(II). Exciplex formation in solution and the solid state [J].
Bencini, A ;
Berni, E ;
Bianchi, A ;
Fornasari, P ;
Giorgi, C ;
Lima, JC ;
Lodeiro, C ;
Melo, MJ ;
de Melo, JS ;
Parola, AJ ;
Pina, F ;
Pina, J ;
Valtancoli, B .
DALTON TRANSACTIONS, 2004, (14) :2180-2187
[4]   Chemically stable films for combinatorial fluorosensor arrays [J].
Benko, A ;
Prince, M ;
Price, BJ ;
Kaltcheva, NT ;
Geissinger, P ;
Schwabacher, AW .
JOURNAL OF COMBINATORIAL CHEMISTRY, 2006, 8 (02) :221-227
[5]   The electronic tongue and ATR-FTIR for rapid detection of sugars and acids in tomatoes [J].
Beullens, Katrien ;
Kirsanov, Dmitriy ;
Irudayaraj, Joseph ;
Rudnitskaya, Alisa ;
Legin, Andrey ;
Nicolai, Bart M. ;
Lammertyn, Jeroen .
SENSORS AND ACTUATORS B-CHEMICAL, 2006, 116 (1-2) :107-115
[6]  
Byfield MP, 1996, GEC-J RES, V13, P17
[7]   SOLVATOCHROMIC STUDIES OF FLUORESCEIN DIANION IN N,N-DIMETHYLFORMAMIDE WATER AND DIMETHYLSULFOXIDE WATER [J].
CHOI, MF ;
HAWKINS, P .
SPECTROSCOPY LETTERS, 1994, 27 (08) :1049-1063
[8]   Characterization of multicomponent monosaccharide solutions using an enzyme-based sensor array [J].
Curey, TE ;
Goodey, A ;
Tsao, A ;
Lavigne, J ;
Sohn, Y ;
McDevitt, JT ;
Anslyn, EV ;
Neikirk, D ;
Shear, JB .
ANALYTICAL BIOCHEMISTRY, 2001, 293 (02) :178-184
[9]   Electronic nose and electronic tongue integration for improved classification of clinical and food samples [J].
Di Natale, C ;
Paolesse, R ;
Macagnano, A ;
Mantini, A ;
D'Amico, A ;
Legin, A ;
Lvova, L ;
Rudnitskaya, A ;
Vlasov, Y .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 64 (1-3) :15-21
[10]   Convergent, self-encoded bead sensor arrays in the design of an artificial nose [J].
Dickinson, TA ;
Michael, KL ;
Kauer, JS ;
Walt, DR .
ANALYTICAL CHEMISTRY, 1999, 71 (11) :2192-2198