Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa

被引:219
作者
Parpia, Alyssa S. [1 ]
Ndeffo-Mbah, Martial L. [1 ]
Wenzel, Natasha S. [1 ]
Galvani, Alison P. [1 ]
机构
[1] Yale Univ, Sch Publ Hlth, New Haven, CT USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
SUB-SAHARAN AFRICA; FALCIPARUM-MALARIA; COST-EFFECTIVENESS; RANDOMIZED-TRIAL; DISEASE; MANAGEMENT; MORTALITY; CHILDREN; GUINEA; BURDEN;
D O I
10.3201/eid2203.150977
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Response to the 2014-2015 Ebola outbreak in West Africa overwhelmed the healthcare systems of Guinea, Liberia, and Sierra Leone, reducing access to health services for diagnosis and treatment for the major diseases that are endemic to the region: malaria, HIV/AIDS, and tuberculosis. To estimate the repercussions of the Ebola outbreak on the populations at risk for these diseases, we developed computational models for disease transmission and infection progression. We estimated that a 50% reduction in access to healthcare services during the Ebola outbreak exacerbated malaria, HIV/AIDS, and tuberculosis mortality rates by additional death counts of 6,269 (2,564-12,407) in Guinea; 1,535 (522-2,8780) in Liberia; and 2,819 (844-4,844) in Sierra Leone. The 2014-2015 Ebola outbreak was catastrophic in these countries, and its indirect impact of increasing the mortality rates of other diseases was also substantial.
引用
收藏
页码:433 / 441
页数:9
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