Transition Metal-Free Synthesis of Carbo- and Heterocycles via Reaction of Alkynes with Organylchalcogenides

被引：14

作者：

Zeni, Gilson ^{[1
]}

Godoi, Benhur ^{[2
]}

Jurinic, Carla K. ^{[2
]}

Belladona, Andrei L. ^{[1
]}

Schumacher, Ricardo F. ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Chem, BR-97105900 Santa Maria, RS, Brazil

[2] Fed Univ Fronteira, Programa Posgrad Ambiente & Tecnol Sustentaveis P, BR-97900000 Fronteira, RS, Brazil

来源：

CHEMICAL RECORD | 2021年 / 21卷 / 10期

关键词：

diselenides; heterocycles; metal-free; alkynes; cyclization; ELECTROPHILIC CYCLIZATION; OXIDATIVE CYCLIZATION; PROMOTED CYCLIZATION; SELENIUM; DISULFIDES; DISELENIDES; ANTIOXIDANT; ANNULATION; CATALYSIS; ACCESS;

D O I：

10.1002/tcr.202000152

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This manuscript intends to overview the most recent advances in the synthesis of carbo- and heterocycles through reactions of alkynes with organyl chalcogenides (S, Se, Te) under metal-free conditions. Firstly, the use of electrophilic chalcogenyl halides as a selective reagent for alkyne carbon-carbon triple bond activation will be presented. After that, radical cyclization protocols employing electrochemical oxidative conditions, light-induced photoredox catalysis, or mild oxidants with direct chalcogenyl group installation will be discussed accompanied by the proposed mechanisms.

引用

页码：2880 / 2895

页数：16

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