Apotirucallane protolimonoids from the Chinese mangrove Xylocarpus granatum Koenig

被引:19
|
作者
Zhou, Zhen-Fang [1 ]
Taglialatela-Scafati, Orazio [2 ]
Liu, Hai-Li [1 ]
Gu, Yu-Cheng [3 ]
Kong, Ling-Yi [4 ]
Guo, Yue-Wei [1 ]
机构
[1] Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
[2] Univ Naples Federico II, Dipartimento Farm, I-80131 Naples, Italy
[3] Syngenta Jealotts Hill Int Res Ctr, Guildford RG42 6EY, Berks, England
[4] China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Peoples R China
关键词
Xylocarpus granatum; Protolimonoid; Apotirucallane; Cytotoxicity; LIMONOIDS;
D O I
10.1016/j.fitote.2014.06.009
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A series of previously unreported compounds including seven new apotirucallane protolimonoids, xylogranatumines A-G (1-7), were isolated together with three known analogues (8-10) from the twigs and leaves of the Chinese mangrove, Xylocarpus granatum. The structures of these new compounds were elucidated by extensive spectroscopic analysis including 1D and 2D NMR and high-resolution electrospray ionization mass spectrometry (HRESIMS) and by comparison with those of related known compounds in the literature. Xylogranatumine F (6) exhibited cytotoxic activity against A549 tumor cell in vitro. (c) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:192 / 197
页数:6
相关论文
共 50 条
  • [1] Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig
    Su, Ming-Zhi
    Zhou, Zhen-Fang
    Guo, Yue-Wei
    CHEMISTRY & BIODIVERSITY, 2023, 20 (08)
  • [2] Bioactive rearranged limonoids from the Chinese mangrove Xylocarpus granatum Koenig
    Zhou, Zhen-Fang
    Liu, Hai-Li
    Zhang, Wen
    Kurtan, Tibor
    Mandi, Attila
    Benyei, Attila
    Li, Jia
    Taglialatela-Scafati, Orazio
    Guo, Yue-Wei
    TETRAHEDRON, 2014, 70 (37) : 6444 - 6449
  • [3] Novel and Neuroprotective Tetranortriterpenoids from Chinese Mangrove Xylocarpus granatum Koenig
    Zhou, Zhen-Fang
    Kurtan, Tibor
    Mandi, Attila
    Gu, Yu-Cheng
    Yao, Li-Gong
    Xin, Guo-Rong
    Li, Xu-Wen
    Guo, Yue-Wei
    SCIENTIFIC REPORTS, 2016, 6
  • [4] Protolimonoids from the seeds of Xylocarpus granatum
    Yin, Baowei
    Huo, Changhong
    Shen, Liru
    Wang, Cui
    Zhao, Lei
    Wang, Yongli
    Shi, Qingwen
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, 37 (03) : 218 - 220
  • [5] Four Phragmalin Orthoesters from the Chinese Mangrove Xylocarpus granatum
    Zhou, Zhen-Fang
    Kong, Ling-Yi
    Kurtan, Tibor
    Liu, Hai-Li
    Mandi, Attila
    Li, Jia
    Gu, Yu-Cheng
    Guo, Yue-Wei
    PLANTA MEDICA, 2014, 80 (11) : 949 - 954
  • [6] Limonoids from the mangrove Xylocarpus granatum
    Wu, Jun
    Xiao, Qiang
    Li, Qingxin
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2006, 34 (11) : 838 - 841
  • [7] Two new mexicanolides from the fruit of the Chinese mangrove Xylocarpus granatum
    Wu, J
    Zhang, S
    Song, Y
    Xiao, ZH
    Xiao, Q
    Lia, QX
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2005, 60 (12): : 1291 - 1294
  • [8] The absolute stereochemistry of protoxylogranatin A -: a new protolimonoid from the seeds of Chinese mangrove Xylocarpus granatum
    Li, Min-Yi
    Wu, Jun
    Zhang, Si
    Xiao, Qiang
    Li, Qing-Xin
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2008, 10 (06) : 503 - 508
  • [9] Protoxylocarpins F-H, Protolimonoids from Seed Kernels of Xylocarpus granatum
    Pudhom, Khanitha
    Sommit, Damrong
    Nuclear, Paulwatt
    Ngamrojanavanich, Nattaya
    Petsom, Amorn
    JOURNAL OF NATURAL PRODUCTS, 2009, 72 (12): : 2188 - 2191
  • [10] Butyrospermol fatty acid esters from the fruit of a Chinese mangrove Xylocarpus granatum
    Wu, Jun
    Li, Minyi
    Xiao, Zhihui
    Zhou, Yuan
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2006, 61 (11): : 1447 - 1449