Copper-Catalyzed Oxidative -Alkylation of -Amino Carbonyl Compounds with Ethers via Dual C(sp3)-H Oxidative Cross- Coupling

被引：121

作者：

Wei, Wen-Ting ^{[1
]}

Song, Ren-Jie ^{[1
]}

Li, Jin-Heng ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 08期

关键词：

alkylation; -amino carbonyl compounds; tert-butyl hydrogen peroxide (TBHP); copper; C(sp3)H functionalization; ethers; C-H BONDS; NATURAL-PRODUCTS; PHOTOINDUCED FORMATION; ASYMMETRIC-SYNTHESIS; DIRECT ARYLATION; ALPHA-ARYLATION; DERIVATIVES; VINYL; ALKENYLATION; CHEMISTRY;

D O I：

10.1002/adsc.201301091

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel copper-catalyzed oxidative alkylation of -amino carbonyl compounds with ethers has been established for the selective synthesis of -etherized -amino carbonyl compounds. This oxidative alkylation is achieved by dual C(sp3)H bond oxidative cross-coupling, and its scope is expanded to -amino ketones, -amino esters and -amino amides.

引用

页码：1703 / 1707

页数：5

共 69 条

[1] Annonaceous acetogenins: Recent progress [J].

Alali, FQ ;

Liu, XX ;

McLaughlin, JL .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (03) :504-540

[2]

[Anonymous], 2013, ANGEW CHEM INT ED, V52, P4453

[3]

[Anonymous], 2008, ANGEW CHEM INT ED, V47, P7497

[4]

[Anonymous], 2012, ANGEW CHEM INT ED, V51, P3066

[5]

[Anonymous], 2010, ANGEW CHEM INT ED, V49, P10181

[6]

[Anonymous], 2008, ANGEW CHEM INT ED, V47, P7075

[7]

[Anonymous], 2014, Angew. Chem

[8]

[Anonymous], 2014, ANGEW CHEM INT EDIT, V53, P74

[9]

[Anonymous], 2006, ANGEW CHEM INT ED, V45, P1949

[10]

[Anonymous], 2012, ANGEW CHEM INT ED, V51, P3453

← 1 2 3 4 5 6 7 →