Genetic pattern of CYP1A1*2A (T>C) gene in patients with colorectal cancer in South Jakarta - Indonesia

被引：0
作者：
Adhiyanto, Chris [1 ]
Nisa, Hoirun [1 ]
Ardini, Witri [1 ]
Harriyati, Zeti [1 ]
Suryani [1 ]
Amu, Dina Adlina [1 ]
Fajar, Kemal A. L. [1 ]
Poniman, Taslim [1 ]
Saunar, Rofi [1 ]
Aditomo, W. [1 ]
机构：
[1] State Islamic Univ UIN Syarif Hidayatullah, Fac Med & Hlth Sci, Jakarta 15419, Indonesia
来源：
PROCEEDINGS OF THE 1ST INTERNATIONAL INTEGRATIVE CONFERENCE ON HEALTH, LIFE AND SOCIAL SCIENCES (ICHLAS 2017) | 2017年 / 10卷
关键词：
CYP1A1*2A; colorectal cancer; Indonesia; LUNG-CANCER; RACIAL-DIFFERENCES; CIGARETTE-SMOKING; CYP1A1; GENOTYPE; POLYMORPHISMS; RISK; SUSCEPTIBILITY; COLON; MSPI;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The information of relationship between genetics and cancer in Indonesia, especially colon cancer, is still limited. This study aimed to determine the genetic pattern of colon cancer allele in Fatmawati Hospital, Jakarta -Indonesia. We conducted a case-control study of 40 colorectal cancer patients and 133 volunteers as controls. We observed CYP1A1*2A alleles using RFLP-PCR method. Three milliliters of blood was used to isolate DNA. Our observation showed of the genetic patterns CYP1A1*2A with the incidence of colorectal cancer showed 17 patients were variant-type homozygote and 12 patients were heterozygote type. In this research shown the common of genotyping type CYP1A1*2A of colorectal cancer from the patients are a homozygous variant type.
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页码：20 / 22
页数：3
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