Genetic and soccer: association of ACTN3 and ACE-I/D genetic polymorphisms in soccer players: Literary review

It has been verified and established that around 66% of the components of the athlete's performance and state are explained by hereditary factors. Two of the most studied genetic polymorphisms in relation to sports performance in the last decade are ACTN3 R577X and ACE I/D. The aim of this study was to summarize the possible associations of both polymorphisms and the performance in soccer players, determining the allelic and genotypic combination that stands out the most in this population and, also, to observe their relationships at the physical and physiological level. In order to complete this study, two phases were carried out, the first one of literature review in databases (Pubmed, Scopus and Sportdiscus) and, the second one which covered the information classification and analysis. The studies show a greater influence of the ACE-D and ACTN-R alleles, and higher presence of the ACE-ID and ACTN-RR genotypes. Subjects with these combinations were found to perform better on speed and strength tests. On the other hand, the ACTN3 polymorphism is directly related to muscle injuries. In conclusion, a relationship between genetic polymorphisms and performance in soccer players could be observed. Genetic components can be integrated as a new component within the characterization of sport and as a tool within a model of identification and detection of talents in youth soccer. In addition, genetic biomarkers could be responsible, in the future, for the study of the risk of injury so that performance in professional soccer is much more optimized.