Metabolic pathway engineering for enhanced biohydrogen production

被引:171
作者
Mathews, Juanita [2 ]
Wang, Guangyi [1 ]
机构
[1] Univ Hawaii, Dept Oceanog, Honolulu, HI 96822 USA
[2] Univ Hawaii, Dept Mol Biosci & Bioengn, Honolulu, HI 96822 USA
关键词
Pathway engineering; Metabolic engineering; Biohydrogen production; FERMENTATIVE HYDROGEN-PRODUCTION; ESCHERICHIA-COLI STRAINS; ACID-FORMATION PATHWAYS; CLOSTRIDIUM-ACETOBUTYLICUM; H-2; PRODUCTION; ANAEROBIC FERMENTATION; MICROBIAL-PRODUCTION; DEHYDROGENASE OVEREXPRESSION; CHLAMYDOMONAS-REINHARDTII; CONTINUOUS CULTURES;
D O I
10.1016/j.ijhydene.2009.05.078
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Hydrogen is an ideal, clean, and potentially sustainable energy carrier for the future due to its abundance and non-polluting nature. Numerous bacteria, cyanobacteria, and algae are capable of producing hydrogen from water, solar energy, and a variety of organic substrates. Improvement of these diverse biochemical pathways is needed in order to make biohydrogen competitive with current production methods. This review summarizes some of the main biological pathways that produce hydrogen and their limiting factors. It also describes how metabolic engineering strategies are being used to overcome these limitations, increase yields, and broaden substrate utilization. (C) 2009 International Association for Hydrogen Energy. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:7404 / 7416
页数:13
相关论文
共 126 条
  • [41] REGULATION OF CLOSTRIDIUM-ACETOBUTYLICUM METABOLISM AS REVEALED BY MIXED-SUBSTRATE STEADY-STATE CONTINUOUS CULTURES - ROLE OF NADH/NAD RATIO AND ATP POOL
    GIRBAL, L
    SOUCAILLE, P
    [J]. JOURNAL OF BACTERIOLOGY, 1994, 176 (21) : 6433 - 6438
  • [42] A new model for the anaerobic fermentation of glycerol in enteric bacteria: Trunk and auxiliary pathways in Escherichia coli
    Gonzalez, Ramon
    Murarka, Abhishek
    Dharmadi, Yandi
    Yazdani, Syed Shams
    [J]. METABOLIC ENGINEERING, 2008, 10 (05) : 234 - 245
  • [43] Molecular characterization and transcriptional analysis of the putative hydrogenase gene of Clostridium acetobutylicum ATCC 824
    Gorwa, MF
    Croux, C
    Soucaille, P
    [J]. JOURNAL OF BACTERIOLOGY, 1996, 178 (09) : 2668 - 2675
  • [44] Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824
    Green, EM
    Boynton, ZL
    Harris, LM
    Rudolph, FB
    Papoutsakis, ET
    Bennett, GN
    [J]. MICROBIOLOGY-SGM, 1996, 142 : 2079 - 2086
  • [45] Improvement of cellulolytic properties of Clostridium cellulolyticum by metabolic engineering
    Guedon, E
    Desvaux, M
    Petitdemange, H
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (01) : 53 - 58
  • [46] Proton translocation coupled to formate oxidation in anaerobically grown fermenting Escherichia coli
    Hakobyan, M
    Sargsyan, H
    Bagramyan, K
    [J]. BIOPHYSICAL CHEMISTRY, 2005, 115 (01) : 55 - 61
  • [47] Biological hydrogen production; fundamentals and limiting processes
    Hallenbeck, PC
    Benemann, JR
    [J]. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2002, 27 (11-12) : 1185 - 1193
  • [48] Photosynthetic biomass and H2 production by green algae:: from bioengineering to bioreactor scale-up
    Hankamer, Ben
    Lehr, Florian
    Rupprecht, Jens
    Mussgnug, Jan H.
    Posten, Clemens
    Kruse, Olaf
    [J]. PHYSIOLOGIA PLANTARUM, 2007, 131 (01) : 10 - 21
  • [49] Hydrogenases in green algae: do they save the algae's life and solve our energy problems?
    Happe, T
    Hemschemeier, A
    Winkler, M
    Kaminski, A
    [J]. TRENDS IN PLANT SCIENCE, 2002, 7 (06) : 246 - 250
  • [50] Sustainable fermentative hydrogen production: challenges for process optimisation
    Hawkes, FR
    Dinsdale, R
    Hawkes, DL
    Hussy, I
    [J]. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2002, 27 (11-12) : 1339 - 1347