Omega 3 Fatty Acid and Skin Diseases

被引：46
作者：
Sawada, Yu [1 ]
Saito-Sasaki, Natsuko [1 ]
Nakamura, Motonobu [1 ]
机构：
[1] Univ Occupat & Environm Hlth, Dept Dermatol, Kitakyushu, Fukuoka, Japan
来源：
FRONTIERS IN IMMUNOLOGY | 2021年 / 11卷
关键词：
ω 3 polyunsaturated fatty acids; resolvin; protectin; maresin; metabolites;
D O I：
10.3389/fimmu.2020.623052
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Humans are exposed to various external environmental factors. Food intake is one of the most influential factors impacting daily lifestyle. Among nutrients obtained from foods, omega-3 polyunsaturated fatty acids (PUFAs) have various beneficial effects on inflammatory diseases. Furthermore, omega-3 PUFA metabolites, including resolvins, are known to demonstrate strong anti-inflammatory effects during allergic and inflammatory diseases; however, little is known regarding the actual impact of these metabolites on skin diseases. In this review, we focused on metabolites that have strong anti-inflammatory actions in various inflammatory diseases, as well as those that present antitumor actions in malignancies, in addition to the actual effect of omega-3 PUFA metabolites on various cells.
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页数：8
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