Web services at the European Bioinformatics Institute-2009

被引:48
作者
Mcwilliam, Hamish [1 ]
Valentin, Franck [1 ]
Goujon, Mickael [1 ]
Li, Weizhong [1 ]
Narayanasamy, Menaka [1 ]
Martin, Jenny [1 ]
Miyar, Teresa [1 ]
Lopez, Rodrigo [1 ]
机构
[1] European Bioinformat Inst, EMBL Outstn, Cambridge CB10 1SD, England
基金
美国国家卫生研究院; 英国惠康基金;
关键词
MULTIPLE SEQUENCE ALIGNMENT; CLUSTAL-W; DATABASE; TOOL; INFORMATION; IDENTIFIER; RESOURCE; ACCURATE; GENOMES; MODELS;
D O I
10.1093/nar/gkp302
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The European Bioinformatics Institute (EMBL-EBI) has been providing access to mainstream databases and tools in bioinformatics since 1997. In addition to the traditional web form based interfaces, APIs exist for core data resources such as EMBL-Bank, Ensembl, UniProt, InterPro, PDB and ArrayExpress. These APIs are based on Web Services (SOAP/REST) interfaces that allow users to systematically access databases and analytical tools. From the user's point of view, these Web Services provide the same functionality as the browser-based forms. However, using the APIs frees the user from web page constraints and are ideal for the analysis of large batches of data, performing text-mining tasks and the casual or systematic evaluation of mathematical models in regulatory networks. Furthermore, these services are widespread and easy to use; require no prior knowledge of the technology and no more than basic experience in programming. In the following we wish to inform of new and updated services as well as briefly describe planned developments to be made available during the course of 2009-2010.
引用
收藏
页码:W6 / W10
页数:5
相关论文
共 36 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]  
ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999
[3]   The Universal Protein Resource (UniProt) 2009 [J].
Bairoch, Amos ;
Consortium, UniProt ;
Bougueleret, Lydie ;
Altairac, Severine ;
Amendolia, Valeria ;
Auchincloss, Andrea ;
Argoud-Puy, Ghislaine ;
Axelsen, Kristian ;
Baratin, Delphine ;
Blatter, Marie-Claude ;
Boeckmann, Brigitte ;
Bolleman, Jerven ;
Bollondi, Laurent ;
Boutet, Emmanuel ;
Quintaje, Silvia Braconi ;
Breuza, Lionel ;
Bridge, Alan ;
deCastro, Edouard ;
Ciapina, Luciane ;
Coral, Danielle ;
Coudert, Elisabeth ;
Cusin, Isabelle ;
Delbard, Gwennaelle ;
Dornevil, Dolnide ;
Roggli, Paula Duek ;
Duvaud, Severine ;
Estreicher, Anne ;
Famiglietti, Livia ;
Feuermann, Marc ;
Gehant, Sebastian ;
Farriol-Mathis, Nathalie ;
Ferro, Serenella ;
Gasteiger, Elisabeth ;
Gateau, Alain ;
Gerritsen, Vivienne ;
Gos, Arnaud ;
Gruaz-Gumowski, Nadine ;
Hinz, Ursula ;
Hulo, Chantal ;
Hulo, Nicolas ;
James, Janet ;
Jimenez, Silvia ;
Jungo, Florence ;
Junker, Vivien ;
Kappler, Thomas ;
Keller, Guillaume ;
Lachaize, Corinne ;
Lane-Guermonprez, Lydie ;
Langendijk-Genevaux, Petra ;
Lara, Vicente .
NUCLEIC ACIDS RESEARCH, 2009, 37 :D169-D174
[4]   The Protein Data Bank [J].
Berman, HM ;
Westbrook, J ;
Feng, Z ;
Gilliland, G ;
Bhat, TN ;
Weissig, H ;
Shindyalov, IN ;
Bourne, PE .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242
[5]   Petabyte-scale innovations at the European Nucleotide Archive [J].
Cochrane, Guy ;
Akhtar, Ruth ;
Bonfield, James ;
Bower, Lawrence ;
Demiralp, Fehmi ;
Faruque, Nadeem ;
Gibson, Richard ;
Hoad, Gemma ;
Hubbard, Tim ;
Hunter, Christopher ;
Jang, Mikyung ;
Juhos, Szilveszter ;
Leinonen, Rasko ;
Leonard, Steven ;
Lin, Quan ;
Lopez, Rodrigo ;
Lorenc, Dariusz ;
McWilliam, Hamish ;
Mukherjee, Gaurab ;
Plaister, Sheila ;
Radhakrishnan, Rajesh ;
Robinson, Stephen ;
Sobhany, Siamak ;
Hoopen, Petra Ten ;
Vaughan, Robert ;
Zalunin, Vadim ;
Birney, Ewan .
NUCLEIC ACIDS RESEARCH, 2009, 37 :D19-D25
[6]   The Ontology Lookup Service:: more data and better tools for controlled vocabulary queries [J].
Cote, Richard G. ;
Jones, Philip ;
Martens, Lennart ;
Apweiler, Rolf ;
Hermjakob, Henning .
NUCLEIC ACIDS RESEARCH, 2008, 36 :W372-W376
[7]   The Protein Identifier Cross-Referencing (PICR) service:: reconciling protein identifiers across multiple source databases [J].
Cote, Richard G. ;
Jones, Philip ;
Martens, Lennart ;
Kerrien, Samuel ;
Reisinger, Florian ;
Lin, Quan ;
Leinonen, Rasko ;
Apweiler, Rolf ;
Hermjakob, Henning .
BMC BIOINFORMATICS, 2007, 8 (1) :401
[8]   LGICdb:: a manually curated sequence database after the genomes [J].
Donizelli, Marco ;
Djite, Marie-Ange ;
Le Novere, Nicolas .
NUCLEIC ACIDS RESEARCH, 2006, 34 :D267-D269
[9]   MUSCLE: a multiple sequence alignment method with reduced time and space complexity [J].
Edgar, RC .
BMC BIOINFORMATICS, 2004, 5 (1) :1-19
[10]  
FelsensteinJ, 1989, PHYLIP (phylogeny inference package) version 3.6, V5, P164