Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions

被引：46

作者：

Mohammadizadeh, Mohammad R. ^{[1
]}

Hasaninejad, Alireza ^{[1
]}

Bahramzadeh, M. ^{[1
]}

机构：

[1] Persian Gulf Univ, Dept Chem, Fac Sci, Bushehr 75169, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 18期

关键词：

Four-component; microwave; solvent-free; tetrasubstituted imidazoles; trifluoroacetic acid; ONE-STEP SYNTHESIS; TETRASUBSTITUTED IMIDAZOLES; HIGHLY-EFFICIENT; SUBSTITUTED IMIDAZOLES; DERIVATIVES; MILD; TFA; 6-AMINOURACILS; REAGENT; SYSTEM;

D O I：

10.1080/00397910902737122

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method for synthesis of various tetrasubstituted imidazoles, using trifluoroacetic acid (TFA) as a catalytic support, by four-component condensation of benzil, aldehydes, amines, and ammonium acetate under microwave-irradiated, solvent-free conditions is described.

引用

页码：3232 / 3242

页数：11

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