Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation

被引：140

作者：

Singh, Harmeet ^{[1
]}

Aplin, John D. ^{[1
]}

机构：

[1] Univ Manchester, Maternal & Fetal Hlth Res Grp, Manchester, Lancs, England

来源：

JOURNAL OF ANATOMY | 2009年 / 215卷 / 01期

关键词：

adhesion; embryo; endometrium; epithelium; implantation; CALCITONIN-GENE EXPRESSION; CARCINOMA-ASSOCIATED ANTIGEN; PREIMPLANTATION HUMAN EMBRYO; MATERNAL-FETAL INTERFACE; E-CADHERIN EXPRESSION; DOUBLE MUTANT MICE; L-SELECTIN LIGAND; CELL-ADHESION; MENSTRUAL-CYCLE; BETA-CATENIN;

D O I：

10.1111/j.1469-7580.2008.01034.x

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Cell adhesion in endometrial epithelium is regulated to maintain the continuity and protectiveness of the luminal covering cell layer while permitting interstitial implantation of the embryo during a restricted period of about 4 days. Many apparently normal embryos fail to implant, and epithelial-embryo adhesion remains a poorly understood phenomenon. After menstruation, epithelial regeneration occurs by epiboly from the basal residues of glands, an activity that requires migration on extracellular matrix as well as cell-cell cohesion. Here we review current knowledge of adhesion molecules in the epithelium.

引用

页码：3 / 13

页数：11

共 166 条

[1] Temporal variation in the distribution of hyaluronic acid, CD44s, and CD44v6 in the human endometrium across the menstrual cycle [J].

Afify, Alaa M. ;

Craig, Sarah ;

Paulino, Augusto F. G. .

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2006, 14 (03) :328-333

[2]

ALBERS A, 1995, ACTA ANAT, V153, P12

[3] Embryo implantation: the molecular mechanism remains elusive [J].

Aplin, J. D. .

REPRODUCTIVE BIOMEDICINE ONLINE, 2006, 13 (06) :833-839

[4]

Aplin J D, 1997, Rev Reprod, V2, P84, DOI 10.1530/revreprod/2.2.84

[5]

APLIN JD, 1991, J REPROD FERTIL, V92, P525

[6] The cell biological basis of human implantation [J].

Aplin, JD .

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2000, 14 (05) :757-764

[7] Bioinformatics and transcriptomics studies of early implantation [J].

Aplin, John D. ;

Singh, Harmeet .

ASSESSMENT OF HUMAN REPRODUCTIVE FUNCTION, 2008, 1127 :116-120

[8]

Aplin John D, 2004, Reprod Biol Endocrinol, V2, P48

[9] Integrins β5, β3 and αv are apically distributed in endometrial epithelium [J].

Aplin, John D. ;

Spanswick, Catherine ;

Behzad, Farhad ;

Kimber, Susan J. ;

Vicovac, Ljiljana .

MOLECULAR HUMAN REPRODUCTION, 1996, 2 (07) :527-527

[10] Osteopontin and its receptor αvβ3 integrin are coexpressed in the human endometrium during the menstrual cycle but regulated differentially [J].

Apparao, KBC ;

Murray, MJ ;

Fritz, MA ;

Meyer, WR ;

Chambers, AF ;

Truong, PR ;

Lessey, BA .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (10) :4991-5000

← 1 2 3 4 5 6 7 8 9 10 →