The role of vitamin D in reproductive dysfunction in women - a systematic review

被引:35
作者
Skowronska, Patrycja [1 ]
Pastuszek, Ewa [1 ,2 ]
Kuczynski, Waldemar [3 ,4 ]
Jaszczol, Mariusz [5 ]
Kuc, Pawel [3 ,4 ]
Jakiel, Grzegorz [6 ,7 ]
Woclawek-Potocka, Izabela [8 ]
Lukaszuk, Krzysztof [1 ,2 ,9 ]
机构
[1] Med Univ Gdansk, Fac Hlth Sci, Dept Obstet & Gynecol Nursing, Debinki 7, PL-80952 Gdansk, Poland
[2] INVICTA Fertil & Reprod Ctr, Gdansk, Poland
[3] Ctr Reprod Med KRIOBANK, Bialystok, Poland
[4] Med Univ Bialystok, Bialystok, Poland
[5] Gdansk Univ Technol, Fac Chem, Dept Chem & Proc Engn, Gdansk, Poland
[6] INVICTA Fertil & Reprod Ctr, Warsaw, Poland
[7] Med Ctr Postgrad Educ, Dept Obstet & Gynaecol 1, Warsaw, Poland
[8] Polish Acad Sci, Inst Anim Reprod & Food Res, Dept Reprod Immunol & Pathol, Olsztyn, Poland
[9] Med Univ Warsaw, Dept Gyneacol Endocrinol, Warsaw, Poland
关键词
vitamin D; PCOS; endometriosis; uterine leiomyomas; in vitro fertilization; POLYCYSTIC OVARIAN SYNDROME; D-BINDING PROTEIN; D DEFICIENCY; UTERINE LEIOMYOMAS; INSULIN-RESISTANCE; FOLLICULAR-FLUID; 1,25-DIHYDROXYVITAMIN D-3; PREGNANCY RATES; SERUM; EXPRESSION;
D O I
10.5604/12321966.1226865
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Vitamin D is essential for the proper functioning of the human body. There is also evidence of its strong association with fertility problems in women. This review aims to evaluate the relationship between vitamin D and diseases affecting women's fertility (polycystic ovarian syndrome (PCOS), uterine leiomyomas and endometriosis), and in vitro fertilization (IVF) outcome. A systematic review of the literature was conducted in Scopus and PubMed for relevant English language publications since 1989. Vitamin D influences the functioning of the reproductive system in women and has been associated with PCOS, uterine leiomyomas, endometriosis and in vitro fertilization (IVF) outcome. However, further studies on larger groups of patients are needed to establish what role vitamin D plays in the treatment of female infertility.
引用
收藏
页码:671 / 676
页数:6
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