Use of Hypervalent Iodine Reagents in Visible Light-Promoted α-Ketoacylations of Sulfoximines with Aryl Alkynes

被引：27

作者：

Wang, Chenyang ^{[1
]}

Ma, Ding ^{[1
]}

Tu, Yongliang ^{[1
]}

Bolm, Carsten ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

ORGANIC LETTERS | 2020年 / 22卷 / 22期

关键词：

D O I：

10.1021/acs.orglett.0c03338

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In visible light, sulfoximidoyl-containing hypervalent iodine reagents react with aryl alkynes to give N-alpha-ketoacylated sulfoximines in good to high yields. The process is metal- and base-free, providing the diketonic products without the use of highly oxygenated reagents such as peroxides. Results from mechanistic investigations suggest the intermediacy of radicals and reveal the importance of molecular oxygen.

引用

页码：8937 / 8940

页数：4

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