Highly Regio- and Enantioselective Copper-Catalyzed Hydroboration of Styrenes

被引：252

作者：

Noh, Dongwan ^{[1
,2
]}

Chea, Heesung ^{[1
,2
]}

Ju, Junghwan ^{[1
,2
]}

Yun, Jaesook ^{[1
,2
]}

机构：

[1] Sungkyunkwan Univ, Dept Chem, Suwon 440746, South Korea

[2] Sungkyunkwan Univ, Inst Basic Sci, Suwon 440746, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 33期

关键词：

asymmetric catalysis; copper; hydroboration; pinacolborane; styrene; ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; ASYMMETRIC HYDROBORATION; BORYL COMPLEXES; BETA-BORATION; ESTERS; REDUCTION; ALKENES; OLEFINS; CU; PINACOLBORANE;

D O I：

10.1002/anie.200902015

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An existing challenge is the development of efficient regioselective catalytic systems that are compatible with stable hydroboration reagents and can be rendered enantioselective by the use of nonracemic ligands. Copper (I) complexes with chelating phosphines catalyzed the regio- and enantioselective hydroboration of styrenes with pinacolborane (PinBH) at room temperature to afford the corresponding branched boronate esters (see example). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6062 / 6064

页数：3

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