Hepatitis E Virus: Current Concepts and Future Perspectives

被引:20
作者
Dalton, Harry R. [1 ,2 ]
Pas, Suzan D. [3 ]
Madden, Richie G. [1 ]
van der Eijk, Annemiek A. [3 ]
机构
[1] Royal Cornwall Hosp Trust, Cornwall Gastrointestinal Unit, Truro TR1 3LJ, England
[2] Univ Exeter, European Ctr Environm & Human Hlth, Sch Med, Truro, England
[3] Univ Med Ctr Rotterdam, Erasmus MC, Dept Virosci, Rotterdam, Netherlands
关键词
Hepatitis E; Zoonosis; Hepatitis; Chronic liver disease; Epidemiology; STEM-CELL TRANSPLANTATION; ALLOGENEIC MARROW TRANSPLANTATION; INDUCED LIVER-INJURY; BLOOD-DONORS; GENOTYPE; NATURAL-HISTORY; E INFECTION; DEVELOPED-COUNTRIES; IGG SEROPREVALENCE; HIGH PREVALENCE;
D O I
10.1007/s11908-014-0399-8
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
For many years, hepatitis E was considered a disease found only in certain developing countries. In these geographical settings, hepatitis E virus (HEV) causes a self-limiting hepatitis in young adults, except in pregnant females, in whom the mortality is 25 %. Our understanding of HEV has changed radically in the past decade. It is now evident that HEV is a threat to global health. This review article considers the current concepts and future perspectives of HEV and its effects on human health, with particular reference to developed countries.
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页数:10
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