Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000

被引:8
作者
Lang, Samantha [1 ]
Schimansky, Sarah [1 ]
Beynon, Rhona [2 ]
Penfold, Christopher [1 ]
Davies, Amy [1 ]
Waylen, Andrea [3 ]
Thomas, Steven [3 ]
Pring, Miranda [3 ]
Pawlita, Michael [4 ]
Waterboer, Tim [5 ]
Ness, Andrew R. [1 ]
机构
[1] Univ Bristol, Natl Inst Hlth NIHR, Bristol Biomed Res Ctr, Nutr Theme, Bristol, Avon, England
[2] Univ Bristol, Med Sch, Dept Populat Hlth Sci, Bristol, Avon, England
[3] Bristol Dent Sch, Dept Oral & Dent Sci, Bristol, Avon, England
[4] German Canc Res Ctr, Mol Diagnost Oncogen Infect Div, Heidelberg, Germany
[5] German Canc Res Ctr, Infect & Canc Epidemiol, Heidelberg, Germany
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2019年 / 41卷 / 07期
关键词
deep-fried food; fruit; head and neck cancers; survival; vegetables; BODY-MASS INDEX; HUMAN-PAPILLOMAVIRUS; ENERGY-INTAKE; FRIED FOODS; RISK-FACTOR; LARYNGEAL; FRUIT; DETERMINANTS; CONSUMPTION; VEGETABLES;
D O I
10.1002/hed.25660
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background The association between diet and head and neck cancer (HNC) survival is unclear. Methods Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status. Results Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13). Conclusions Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.
引用
收藏
页码:2074 / 2084
页数:11
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