An antitumor boost to TH9 cells

被引：10
|
作者：
Quezada, Sergio A. [1 ]
Peggs, Karl S. [1 ]
机构：
[1] UCL, Inst Canc, Dept Res Haematol, Canc Immunol Unit, London, England
来源：
NATURE IMMUNOLOGY | 2014年 / 15卷 / 08期
关键词：
REGULATORY T-CELLS; BETA;
D O I：
10.1038/ni.2945
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Cells of the T(H)9 subset of helper T cells differentiated in the presence of interleukin 1 beta (IL-1 beta) produce large amounts of IL-9 and IL-21 in a manner dependent on the transcription factors STAT1 and IRF1 and exhibit potent anticancer effects.
引用
收藏
页码：703 / 705
页数：4
相关论文
共 50 条
  • [21] Transcriptome profiling of human Th9 cells
    Parmentier, C.
    Cousins, D.
    IMMUNOLOGY, 2011, 135 : 80 - 80
  • [22] The Unique Features of Th9 Cells and their Products
    Tan, Cuiyan
    Gery, Igal
    CRITICAL REVIEWS IN IMMUNOLOGY, 2012, 32 (01) : 1 - 10
  • [23] Inflammed Skin Harbours Th9 Cells
    Cortelazzi, Chiara
    Campanini, Nicoletta
    Ricci, Roberto
    De Panfilis, Giuseppe
    ACTA DERMATO-VENEREOLOGICA, 2013, 93 (02) : 183 - 185
  • [24] Differentiation, Regulation and Function of Th9 Cells
    Jia, Lei
    Wu, Changyou
    T HELPER CELL DIFFERENTIATION AND THEIR FUNCTION, 2014, 841 : 181 - 207
  • [25] The transcription factor network in Th9 cells
    Mark H. Kaplan
    Seminars in Immunopathology, 2017, 39 : 11 - 20
  • [26] Harnessing TH9 cells in cancer immunotherapy
    Benoit-Lizon, Isis
    Apetoh, Lionel
    SEMINARS IN IMMUNOLOGY, 2021, 52
  • [27] TH9 cells creep under the skin
    Kugelberg, Elisabeth
    NATURE REVIEWS IMMUNOLOGY, 2014, 14 (03) : 138 - 139
  • [28] DECREASED TH9 AND IMBALANCE OF TH9 AND TH17 IN SPONDYLOARTHROPATHY
    Ryu, H. J.
    Lee, M. K.
    Seo, M. R.
    Choi, H. J.
    Baek, H. J.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2014, 32 (05) : 806 - 806
  • [29] The transcription factor network in Th9 cells
    Kaplan, Mark H.
    SEMINARS IN IMMUNOPATHOLOGY, 2017, 39 (01) : 11 - 20
  • [30] TH9 cells tackle advanced tumours
    Alexandra Flemming
    Nature Reviews Immunology, 2018, 18 : 479 - 479
12345