An antitumor boost to TH9 cells

被引：10
|
作者：
Quezada, Sergio A. [1 ]
Peggs, Karl S. [1 ]
机构：
[1] UCL, Inst Canc, Dept Res Haematol, Canc Immunol Unit, London, England
来源：
NATURE IMMUNOLOGY | 2014年 / 15卷 / 08期
关键词：
REGULATORY T-CELLS; BETA;
D O I：
10.1038/ni.2945
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Cells of the T(H)9 subset of helper T cells differentiated in the presence of interleukin 1 beta (IL-1 beta) produce large amounts of IL-9 and IL-21 in a manner dependent on the transcription factors STAT1 and IRF1 and exhibit potent anticancer effects.
引用
收藏
页码：703 / 705
页数：4
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