Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

被引：50

作者：

Zhang, Hailong ^{[1
]}

Ma, Yong ^{[1
]}

Sun, Xue-Long ^{[1
]}

机构：

[1] Cleveland State Univ, Dept Chem, Cleveland, OH 44115 USA

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 21期

关键词：

DERIVATIVES; PROTEIN;

D O I：

10.1039/b822420j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBS buffer (pH 7.4) at room temperature.

引用

页码：3032 / 3034

页数：3

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