Cell growth: Downstream of Myc - to grow or to cycle?

被引:40
作者
Elend, M [1 ]
Eilers, M [1 ]
机构
[1] Inst Mol Biol & Tumorforsch, D-35037 Marburg, Germany
关键词
D O I
10.1016/S0960-9822(00)80109-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
For many years, Myc function has been linked to the control of cell-cycle progression. Now, increasing evidence shows that Myc also controls cell growth, and that these two processes are regulated independently, (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:R936 / R938
页数:3
相关论文
共 20 条
[1]  
Amati Bruno, 1998, Frontiers in Bioscience, V3, pD250
[2]   Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27 [J].
Bouchard, C ;
Thieke, K ;
Maier, A ;
Saffrich, R ;
Hanley-Hyde, J ;
Ansorge, W ;
Reed, S ;
Sicinski, P ;
Bartek, J ;
Eilers, M .
EMBO JOURNAL, 1999, 18 (19) :5321-5333
[3]   A new pathway for mitogen-dependent Cdk2 regulation uncovered in p27Kip1-deficient cells [J].
Coats, S ;
Whyte, P ;
Fero, ML ;
Lacy, S ;
Chung, G ;
Randel, E ;
Firpo, E ;
Roberts, JM .
CURRENT BIOLOGY, 1999, 9 (04) :163-173
[4]   Size control in animal development [J].
Conlon, I ;
Raff, M .
CELL, 1999, 96 (02) :235-244
[5]  
Dang CV, 1999, MOL CELL BIOL, V19, P1
[6]   Cdc25 cell-cycle phosphatase as a target of c-myc [J].
Galaktionov, K ;
Chen, XC ;
Beach, D .
NATURE, 1996, 382 (6591) :511-517
[7]   c-Myc enhances protein synthesis and cell size during B lymphocyte development [J].
Iritani, BM ;
Eisenman, RN .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (23) :13180-13185
[8]   DIFFERENTIAL MODULATION OF CYCLIN GENE-EXPRESSION BY MYC [J].
JANSENDURR, P ;
MEICHLE, A ;
STEINER, P ;
PAGANO, M ;
FINKE, K ;
BOTZ, J ;
WESSBECHER, J ;
DRAETTA, G ;
EILERS, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) :3685-3689
[9]   Drosophila myc regulates cellular growth during development [J].
Johnston, LA ;
Prober, DA ;
Edgar, BA ;
Eisenman, RN ;
Gallant, P .
CELL, 1999, 98 (06) :779-790
[10]   Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F [J].
Leone, G ;
DeGregori, J ;
Sears, R ;
Jakoi, L ;
Nevins, JR .
NATURE, 1997, 387 (6631) :422-426