Effects of resistance training on liver structure and function of aged rats

被引：5

作者：

Baptista Nucci, Ricardo Aparecido ^{[1
]}

de Souza Teodoro, Ana Caroline ^{[1
]}

Krause Neto, Walter ^{[2
]}

Silva, Wellington de Assis ^{[2
]}

de Souza, Romeu Rodrigues ^{[1
,2
]}

Anaruma, Carlos Alberto ^{[3
]}

Gama, Eliane Florencio ^{[1
,2
]}

机构：

[1] Univ Sao Judas Tadeu, Dept Aging Sci, 546 Taquari St, Sao Paulo, Brazil

[2] Univ Sao Judas Tadeu, Dept Phys Educ, Sao Paulo, Brazil

[3] Julio de Mesquita Filho Sao Paulo State Univ, Dept Phys Educ, Sao Paulo, Brazil

来源：

AGING MALE | 2018年 / 21卷 / 01期

关键词：

Liver; aging; resistance training; hepatic structure; exercise; OLDER-ADULTS; BLOOD-FLOW; EXERCISE; METAANALYSIS; INTENSITY; HYPERTROPHY; PREVENTION; RESPONSES; DEMENTIA; STRENGTH;

D O I：

10.1080/13685538.2017.1350157

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aging process may cause negative physiological changes. However, exercises as resistance training (RT) have been considered an important intervention to attenuate these changes. Additionally, liver plays an important role in blood glucose homeostasis in exercise.Aim: This study aimed to analyze the effects of RT on the liver components of aged animals.Methods: Male Wistar rats were divided into two groups: 24 months' group (CONTROL); and group submitted to a progressive RT protocol for 16 weeks (EXERCISE). Both groups were sacrificed at 24 months.Results: We observed a decrease in blood flow due to the practice of resistance exercises. Besides, our results showed that hepatic tissue plays an important role in glycemic homeostasis during RT. In addition, RT increased mitogen capacity of hepatocytes.Conclusions: Our study showed many implications for the knowledge about the effects of strength training on old animals' liver.

引用

页码：60 / 64

页数：5

共 34 条

[1] Effects of testosterone administration on liver structure and function in aging rats [J].

Baptista Nucci, Ricardo Aparecido ;

de Souza Teodoro, Ana Caroline ;

Neto, Walter Krause ;

Silva, Wellington de Assis ;

de Souza, Romeu Rodrigues ;

Anaruma, Carlos Alberto ;

Gama, Eliane Florencio .

AGING MALE, 2017, 20 (02) :134-137

[2] INCREASED ENERGY-REQUIREMENTS AND CHANGES IN BODY-COMPOSITION WITH RESISTANCE TRAINING IN OLDER ADULTS [J].

CAMPBELL, WW ;

CRIM, MC ;

YOUNG, VR ;

EVANS, WJ .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1994, 60 (02) :167-175

[3] Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials [J].

Chang, JT ;

Morton, SC ;

Rubenstein, LZ ;

Mojica, WA ;

Maglione, M ;

Suttorp, MJ ;

Roth, EA ;

Shekelle, PG .

BRITISH MEDICAL JOURNAL, 2004, 328 (7441) :680-683

[4] Influence of high-intensity exercise training and anabolic androgenic steroid treatment on rat tissue glycogen content [J].

Cunha, TS ;

Tanno, AP ;

Moura, MJCS ;

Marcondes, FK .

LIFE SCIENCES, 2005, 77 (09) :1030-1043

[5]

DAVIES K J A, 1986, Journal of Free Radicals in Biology and Medicine, V2, P155, DOI 10.1016/S0748-5514(86)80066-6

[6] Exercise training guidelines for the elderly [J].

Evans, WJ .

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1999, 31 (01) :12-17

[7] Oxidants, oxidative stress and the biology of ageing [J].

Finkel, T ;

Holbrook, NJ .

NATURE, 2000, 408 (6809) :239-247

[8]

Fontana K, 2008, HISTOL HISTOPATHOL, V23, P1367, DOI 10.14670/HH-23.1367

[9] Aetiology of running-related gastrointestinal dysfunction - How far is the finishing line? [J].

Gil, SM ;

Yazaki, E ;

Evans, DF .

SPORTS MEDICINE, 1998, 26 (06) :365-378

[10] Resistance exercise and testosterone treatment alters the proportion of numerical density of capillaries of the left ventricle of aging Wistar rats [J].

Goncalves, Leandro ;

de Souza, Romeu Rodrigues ;

Messiano Maifrino, Laura Beatriz ;

Caperuto, Erico Chagas ;

Carbone, Patricia Oliva ;

Rodrigues, Bruno ;

Gama, Eliane Florencio .

AGING MALE, 2014, 17 (04) :243-247

← 1 2 3 4 →