Are ultrashort x-ray pulses likely to be less carcinogenic?

被引:0
作者
Waynant, RW [1 ]
Ilev, IK [1 ]
Mitra, K [1 ]
机构
[1] US FDA, Ctr Devices & Radiol Hlth, Electroopt Branch, Rockville, MD 20857 USA
来源
LASERS IN SURGERY: ADVANCED CHARACTERIZATION, THERAPEUTICS, AND SYSTEMS XIV | 2004年 / 5312卷
关键词
ultrashort; x-ray; carcinogenisis; breath analysis;
D O I
10.1117/12.528234
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
With the development of femtosecond and shorter pulsewidth lasers and the ability to amplify these pulses to incredibly high pulsed power has come the ability to produce ultrashort pulses of x-rays. In previous years sessions of this conference we have proposed use of these ultrashort pulses of x-rays to produce high resolution, high image quality three dimensional x-ray images of breast and other areas of the body. Theoretical studies of the impact of increasing higher power of UV and X-Ray sources for sterilization lead us to question whether very short pulses of extremely high power (but low dose, i.e. J/cm2) may have less carcinogenic effect. If this is true, it could potentially allow greater use of such x-ray systems for breast cancer surveillance as well as other areas such as deep body inspection. In addition, it could allow for creation of better images by use of higher resolution, noise reduction and higher repetition rates. Better images should improve detection.
引用
收藏
页码:267 / 272
页数:6
相关论文
共 13 条
[1]  
Attwood D. T., 2000, SOFT XRAYS EXTREME U
[2]   The effect of high-dose-rate X-rays on E-coli O157:H7 in ground beef [J].
Curry, RD ;
Unklesbay, K ;
Unklesbay, N ;
Clevenger, TE ;
Brazos, BJ ;
Mesyats, G ;
Filatov, A .
IEEE TRANSACTIONS ON PLASMA SCIENCE, 2000, 28 (01) :122-127
[3]   Real-time monitoring of ethane in human breath using mid-infrared cavity leak-out spectroscopy [J].
Dahnke, H ;
Kleine, D ;
Hering, P ;
Mürtz, M .
APPLIED PHYSICS B-LASERS AND OPTICS, 2001, 72 (08) :971-975
[4]   TIME-GATED IMAGING WITH AN ULTRASHORT-PULSE, LASER-PRODUCED-PLASMA X-RAY SOURCE [J].
GORDON, CL ;
YIN, GY ;
LEMOFF, BE ;
BELL, PM ;
BARTY, CPJ .
OPTICS LETTERS, 1995, 20 (09) :1056-1058
[5]  
Herzberg G., 1950, MOL SPECTRA MOL STRU
[6]   A simple submicron confocal microscope with a fiberoptic output [J].
Ilev, IK ;
Waynant, RW .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2000, 71 (11) :4161-4164
[7]   Dual-confocal fiber-optic method for absolute measurement of refractive index and thickness of optically transparent media [J].
Ilev, IK ;
Waynant, RW ;
Byrnes, KR ;
Anders, JJ .
OPTICS LETTERS, 2002, 27 (19) :1693-1695
[8]   Ultrahigh-intensity lasers: Physics of the extreme on a tabletop [J].
Mourou, GA ;
Barty, CPJ ;
Perry, MD .
PHYSICS TODAY, 1998, 51 (01) :22-28
[9]   Clinical application of breath biomarkers of oxidative stress status [J].
Risby, TH ;
Sehnert, SS .
FREE RADICAL BIOLOGY AND MEDICINE, 1999, 27 (11-12) :1182-1192
[10]  
TILLMAN C, 1995, APPL PHYS B, V61, P33