Activation of FGFR-signaling mediates resistance of gastrointestinal stromal tumors (GISTs) to imatinib (IM)

被引：0
作者：
Garanina, E. [1 ]
Boichuk, S. [2 ]
Dunaev, P. [2 ]
Galembikova, A. [2 ]
Shagimardanova, E. [1 ]
Gusev, O. [1 ]
Khaiboullina, S. [1 ]
机构：
[1] Kazan Fed Univ, Kazan, Russia
[2] Kazan State Med Univ, Kazan, Russia
来源：
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 2018年 / 48卷
基金：
俄罗斯科学基金会;
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P071-F
引用
收藏
页码：159 / 159
页数：1
相关论文
共 50 条
[11]   Gastrointestinal stromal tumors (GISTs) [J].
Saund, MS ;
Demetri, GD ;
Ashley, SW .
CURRENT OPINION IN GASTROENTEROLOGY, 2004, 20 (02) :89-94
[12]   Molecular correlates ofsunitinib resistance in gastrointestinal stromal tumors (GISTS) [J].
Fletcher, J. ;
Corless, C. ;
Liegl, B. ;
Fletcher, C. ;
Raut, C. ;
Donsky, R. ;
Bertagnolli, M. ;
Hadow, A. ;
Demetri, G. ;
Heinrich, M. .
ANNALS OF ONCOLOGY, 2007, 18 :VII15-VII16
[13]   KIT mutations and sunitinib resistance in gastrointestinal stromal tumors (GISTs) [J].
Fletcher, J. A. ;
Corless, C. L. ;
Liegl, B. ;
Fletcher, C. D. ;
Raut, C. P. ;
Donsky, R. ;
Bertagnolli, M. M. ;
Harlow, A. ;
Demetri, G. D. ;
Heinrich, M. C. .
EJC SUPPLEMENTS, 2007, 5 (04) :403-403
[14]   GASTROINTESTINAL STROMAL TUMOURS (GISTS) AND LATE RESISTANCE TO IMATINIB MESYLATE (IM): MIGHT HIGHER DOSES HAVE A ROLE IN OVERCOMING RESISTANCE? [J].
Ciccarese, M. ;
Ferraresi, V. ;
Gelibter, A. ;
Zeuli, M. ;
Cognetti, F. .
ANNALS OF ONCOLOGY, 2004, 15 :73-74
[15]   FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors [J].
Li, Fang ;
Huynh, Hung ;
Li, Xiaoyan ;
Ruddy, David A. ;
Wang, Youzhen ;
Ong, Richard ;
Chow, Pierce ;
Qiu, Shumei ;
Tam, Angela ;
Rakiec, Daniel P. ;
Schlegel, Robert ;
Monahan, John E. ;
Huang, Alan .
CANCER DISCOVERY, 2015, 5 (04) :438-451
[16]   Gastrointestinal stromal tumors (GISTs): a review [J].
Steigen, Sonja E. ;
Eide, Tor J. .
APMIS, 2009, 117 (02) :73-86
[17]   Gastrointestinal stromal tumors (GISTs) of the colon [J].
Macias Garcia, F. ;
Parada, P. ;
Martinez-Lesquereux, L. ;
Pintos, E. ;
Fraga, M. ;
Dominguez Munoz, J. E. .
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS, 2010, 102 (06) :388-390
[18]   Surgical intervention following imatinib treatment in patients with advanced gastrointestinal stromal tumors (GISTs) [J].
Sym, Sun Jin ;
Ryu, Min-Hee ;
Lee, Jae-Lyun ;
Chang, Heung Moon ;
Kim, Tae-Won ;
Kim, Hee Cheol ;
Kim, Ki Hun ;
Yook, Jeong Hwan ;
Kim, Byung Sik ;
Kang, Yoon-Koo .
JOURNAL OF SURGICAL ONCOLOGY, 2008, 98 (01) :27-33
[19]   Imatinib Dosing in Gastrointestinal Stromal Tumors (GISTs): When, How Much, and How Long? [J].
Milhem, Mohammed ;
Deutsch, Jeremy M. .
CURRENT CLINICAL PHARMACOLOGY, 2015, 10 (04) :311-320
[20]   The role of surgery in the management of gastrointestinal stromal tumors (GISTs) in the era of imatinib mesylate effectiveness [J].
Kosmadakis, N ;
Visvardis, EE ;
Kartsaklis, P ;
Tsimara, M ;
Chatziantoniou, A ;
Panopoulos, L ;
Erato, P ;
Capsambelis, P .
SURGICAL ONCOLOGY-OXFORD, 2005, 14 (02) :75-84
12345