The growing availability of digital learning materials and their integration in many facets of the education system have created a need for evaluating the accessibility and usability of e-learning materials. In some cases, these digital resources are simple conversions of the original, printed materials into electronic formats. In other cases, the digital versions of the materials take advantage of the interactive abilities of the online and electronic media to enhance students' learning experiences. Regardless of format, however, the content needs to be accessible. Although accessibility guidelines and accessibility evaluations tools are available to users, there is no comprehensive accessibility evaluation technique to help guide users in selecting the most accessible learning materials. In this study, we surveyed existing accessibility tools, selected a recommended tool set, and created a manual for post-secondary educators, students, and other stakeholders to use for evaluating the accessibility of e-textbooks.