Acanthopanax henryi: Review of Botany, Phytochemistry and Pharmacology

被引:28
作者
Li, Xiao-Jun [1 ]
Tang, Si-Qi [1 ]
Huang, Hao [1 ]
Luo, Jiao [2 ]
Zhang, Xiao-Dan [3 ]
Yook, Chang-Soo [4 ]
Whang, Wan-Kyunn [5 ]
Kim, Youn-Chul [6 ]
Liu, Xiang-Qian [2 ]
机构
[1] Gannan Med Univ, Sch Pharm, Natl Engn Res Ctr Modernizat Tradit Chinese Med, Hakka Med Resources Branch, Ganzhou 341000, Peoples R China
[2] Hunan Univ Chinese Med, Sch Pharm, Changsha 410208, Peoples R China
[3] Zhejiang Sci Tech Univ, Coll Life Sci, Hangzhou 310018, Peoples R China
[4] Kyung Hee Univ, Sch Pharm, Seoul 130701, South Korea
[5] Chung Ang Univ, Dept Global Innovat Drugs, Grad Sch, Seoul 156756, South Korea
[6] Wonkwang Univ, Coll Pharm, Iksan 54538, South Korea
来源
MOLECULES | 2021年 / 26卷 / 08期
关键词
Acanthopanax henryi; Eleutherococcus henryi; botany; phytochemistry; pharmacology; biological activities; CHEMICAL-CONSTITUENTS; OLIV; HARMS; LEAVES; SESAMIN;
D O I
10.3390/molecules26082215
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Acanthopanax henryi (Oliv.) Harms (Araliaceae), also known as Eleutherococcus henryi and Caoyewujia (Hengliwujia) in Chinese, is a widely used traditional Chinese herb with the effects of expelling wind and removing dampness, relaxing the muscles and stimulating the blood circulation, and regulating the flow of qi to alleviate pain in the theory of Traditional Chinese Medicine. Acanthopanax henryi (AH, thereafter) possesses ginseng-like activities and is known as ginseng-like herb. In the past decade, a great number of phytochemical and pharmacological studies on AH have been carried out. Several kinds of chemical compositions have been reported, including terpenoids (monoterpenoids, diterpenoids, and triterpenoid saponins), phenylpropanoids, caffeoyl quinic acid derivatives, flavonoids, lignans, sterols, fatty acids, etc., among which, triterpenoid saponins were considered to be the most active components. Considerable pharmacological experiments in vitro have demonstrated that AH possessed anti-neuroinflammatory, anti-adipogenic, anti-inflammatory, antibacterial, anti-cancer, anti-oxidation, anti-AChE, anti-BuChE, and antihyaluronidase activities. The present review is an up-to-date and comprehensive analysis of the botany, phytochemistry, and pharmacology of AH.
引用
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页数:19
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