Assessment of fracture risk

被引：116

作者：

Kanis, John A. ^{[1
]}

Johansson, Helena ^{[1
]}

Oden, Anders ^{[1
]}

McCloskey, Eugene V. ^{[1
,2
]}

机构：

[1] Univ Sheffield, Sch Med, WHO Collaborating Ctr Metab Bone Dis, Sheffield S10 2RX, S Yorkshire, England

[2] No Gen Hosp, Osteoporosis Ctr, Sheffield S5 7AU, S Yorkshire, England

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2009年 / 71卷 / 03期

关键词：

Fracture; Bone mineral density (BMD); Osteoporosis; FRAX (R); T-score; BONE-MINERAL DENSITY; HIP FRACTURE; OSTEOPOROSIS; PROBABILITIES; METAANALYSIS; PREDICTORS; DIAGNOSIS; MASS;

D O I：

10.1016/j.ejrad.2008.04.061

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Fractures are a common complication of osteoporosis. Although osteoporosis is defined by bone mineral density at the femoral neck, other sites and validated techniques can be used for fracture prediction. Several clinical risk factors contribute to fracture risk independently of BMD. These include age, prior fragility fracture, smoking, excess alcohol, family history of hip fracture, rheumatoid arthritis and the use of oral glucocorticoids. These risk factors in conjunction with BMD can be integrated to provide estimates of fracture probability using the FRAX (R) tool. Fracture probability rather than BMD alone can be used to fashion strategies for the assessment and treatment of osteoporosis. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：392 / 397

页数：6

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