The NIR determination of ascorbic acid in pharmaceuticals

被引：0
|
作者：
Zalewska, Malgorzata
Olszanowski, Andrzej
Dlugosz, Monika
机构：
[1] Politechn Poznanska, Inst Inzynierii & Technol Chem, PL-60965 Poznan, Poland
[2] GlaxoSmithKline Pharmaceut SA, Poznan, Poland
来源：
PRZEMYSL CHEMICZNY | 2006年 / 85卷 / 8-9期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The 10,000-4,000 cm(-1) spectra recorded in the reflectance mode were used to detect and det. ascorbic acid in intact tablets of 5 com. prepns. The NIR data compared well with those found by TLC and potentiometric iodometry used as the ret. methods. Full qual. and quant. assay took 30 min, a test time acceptable for large-lot production. Each app. to be used in series measurements requires an individual quant procedure.
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页码：691 / 694
页数：4
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