Imaging protons in molecular compounds and pharmaceuticals using time-of-flight single crystal neutron diffraction

The dramatic advances in instrumentation for single crystal neutron diffraction are reviewed. These promise to revolutionise this area, making the method increasingly attractive and accessible as a complementary tool to X-ray diffraction studies. In particular the possibilities offered by advances in time-of-flight single crystal neutron diffraction methods are discussed. Some of the applications of neutron single crystal diffraction on the SXD instrument at the ISIS source in imaging protons in molecular and pharmaceutical compounds are reviewed, the unique input offered by the use of neutron diffraction being stressed.The dramatic advances in instrumentation for single crystal neutron diffraction are reviewed. These promise to revolutionise this area, making the method increasingly attractive and accessible as a complementary tool to X-ray diffraction studies. In particular the possibilities offered by advances in time-of-flight single crystal neutron diffraction methods are discussed. Some of the applications of neutron single crystal diffraction on the SXD instrument at the ISIS source in imaging protons in molecular and pharmaceutical compounds are reviewed, the unique input offered by the use of neutron diffraction being stressed.