Genetic renal mechanisms of hypertension

被引:7
|
作者
Cusi, D [1 ]
机构
[1] UNIV MILAN,OSPED SAN RAFFAELE,POSTGRAD SCH NEPHROL,I-20132 MILAN,ITALY
来源
关键词
D O I
10.1097/00041552-199703000-00014
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
An update on renal genetic mechanisms of spontaneous hypertension in rats and in human essential hypertension is presented. The findings are discussed, highlighting the search of a possible link between the discovered genetic abnormality and the renal function changes that may determine the disease. The analogies (and/or differences) between the numerous positive findings obtained in animal models and the relatively scarce ones obtained in humans are discussed.
引用
收藏
页码:192 / 198
页数:7
相关论文
共 50 条
  • [1] Renal genetic mechanisms of essential hypertension
    Manunta, P
    Cerutti, R
    Bernardi, L
    Stella, P
    Bianchi, G
    JOURNAL OF NEPHROLOGY, 1997, 10 (04) : 172 - 178
  • [2] Genetic determinants and renal mechanisms in essential hypertension
    Manunta, P
    DelVecchio, L
    Amar, K
    Bianchi, G
    JOURNAL OF HUMAN HYPERTENSION, 1996, 10 (10) : 649 - 656
  • [3] Recent aspects in the genetic renal mechanisms involved in hypertension
    Satoh, T
    Owada, S
    Ishida, M
    INTERNAL MEDICINE, 1999, 38 (12) : 919 - 926
  • [4] RENAL MECHANISMS AND CALCIUM IN THE PATHOGENESIS OF A TYPE OF GENETIC-HYPERTENSION
    BIANCHI, G
    SALVATI, P
    FERRARI, P
    VEZZOLI, G
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1986, 8 : S124 - S129
  • [5] Renal mechanisms of hypertension
    Mattson, DL
    Cowley, AW
    CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 1999, 8 (02): : 217 - 224
  • [6] MECHANISMS IN RENAL HYPERTENSION
    LEDINGHAM, JM
    PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1971, 64 (04): : 409 - +
  • [7] Renal proximal tubule sodium transport and genetic mechanisms of essential hypertension
    Doris, PA
    JOURNAL OF HYPERTENSION, 2000, 18 (05) : 509 - 519
  • [8] Renal mechanisms of genetic hypertension: From the molecular level to the intact organism
    Cusi, D
    Bianchi, G
    KIDNEY INTERNATIONAL, 1996, 49 (06) : 1754 - 1759
  • [9] Calcium signaling mechanisms in renal vascular responses to vasopressin in genetic hypertension
    Feng, JJ
    Arendshorst, WJ
    HYPERTENSION, 1997, 30 (05) : 1223 - 1231
  • [10] Genetic mechanisms of hypertension
    Allison S.
    Nature Reviews Nephrology, 2021, 17 (7) : 437 - 437