Toxicity, Biomarkers, Genotoxicity, and Carcinogenicity of Trichloroethylene and Its Metabolites: A Review

被引：33
作者：
Tabrez, Shams [1 ]
Ahmad, Masood [1 ]
机构：
[1] Aligarh Muslim Univ, Fac Life Sci, Dept Biochem, Aligarh 202002, Uttar Pradesh, India
来源：
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS | 2009年 / 27卷 / 03期
关键词：
Trichloroethylene; biomarker; toxicity; cancer; genotoxicity; SISTER-CHROMATID EXCHANGES; LIVER-TUMOR INDUCTION; TRICHLOROACETIC-ACID; DICHLOROACETIC ACID; INHALATION EXPOSURE; SPECIES-DIFFERENCES; GENETIC TOXICOLOGY; PRIMARY CULTURES; CHLORAL HYDRATE; TISSUE-REPAIR;
D O I：
10.1080/10590500903091340
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Trichloroethylene (TCE) is a prevalent occupational and environmental contaminant that has been reported to cause a variety of toxic effects. This article reviews toxicity, mutagenicity, and carcinogenicity caused by the exposure of TCE and its metabolites in the living system as well as on their (TCE and its metabolites) toxicity biomarkers.
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页码：178 / 196
页数：19
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