Synthesis of 3,6-Divinyl-1,2,4,5-Tetrazine, the First Member of the Elusive Vinyltetrazine Family

被引：5

作者：

Pican, Stephanie ^{[1
]}

Lapinte, Vincent ^{[1
,3
]}

Pilard, Jean-Francois ^{[1
]}

Pasquinet, Eric ^{[2
]}

Beller, Lionel ^{[2
]}

Fontaine, Laurent ^{[1
]}

Poullain, Didier ^{[2
]}

机构：

[1] Univ Maine, CNRS, UMR6011, UCO2M Chim Polymeres, F-72085 Le Mans 09, France

[2] LE RIPAULT, DAM, CEA, F-37260 Monts, France

[3] Univ Montpellier 2, CNRS, UMR5253, IAM,Inst Charles Gerhardt Montpellier, F-34095 Montpellier 5, France

来源：

SYNLETT | 2009年 / 05期

关键词：

azo compounds; condensation; cyclizations; fused ring systems; heterocycles; DIELS-ALDER REACTIONS; SUBSTITUTED TETRAZINES; ANTITUMOR-ACTIVITY; SULFONES; 1,2,4,5-TETRAZINES; DERIVATIVES; CYCLOADDITIONS; BASE;

D O I：

10.1055/s-0028-1087818

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the first vinyltetrazine derivative is described. 3,6-Divinyl-1,2,4,5-tetrazine was obtained following a methodology involving cyclization from ail imidate and use of 2-phenylsulfonylethyl groups as masked vinyl entities. The first properties of this unique compound are reported.

引用

页码：731 / 734

页数：4

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