Recent Developments on the Total Synthesis of Nakadomarin A

被引：2

作者：

Jana, Samaresh ^{[1
]}

Mekonnen, Habtamu Gelaw ^{[1
]}

机构：

[1] KIIT, Sch Appl Sci, Dept Chem, Bhubaneswar 751024, Odisha, India

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 18期

关键词：

Cascade reaction; Diels-Alder reaction; 3+2]-Dipolar cycloaddition; Manzamine alkaloid; Nakadomarin A; Ring Closing Metathesis; Total synthesis; RING-CLOSING METATHESIS; TETRACYCLIC CORE; STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC-SYNTHESIS; ADDITION-REACTIONS; ALKYNE METATHESIS; (-)-NAKADOMARIN; EFFICIENT; COMPLEXES; MANZAMINE;

D O I：

10.1002/slct.201800183

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(-)-Nakadomarin A is an alkaloid belongs to manzamine family having architecturally complex structure and exhibits promising biological activities. To accomplish this target molecule, few novel synthetic strategies have been developed by eminent synthetic chemists. This review will highlight the important and improved synthetic approaches for the total synthesis of natural as well as unnatural isomers of nakadomarin A. All synthetic strategies have been enlightened from the cluster of literatures to develop a more elegant strategy for the molecule in future.

引用

页码：5198 / 5206

页数：9

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