Illuminating molecular processes in living cells

被引:4
作者
Umezawa, Yoshio [1 ]
机构
[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan
关键词
cellular signaling; FRET (fluorescence resonant energy transfer); imaging agents; optical probes; phosphorylation;
D O I
10.1002/asia.200600063
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lately, scientists have explored approaches to developing fluorescent and/or bioluminescent indicators to pinpoint cellular processes in single living cells. These analytical methods have become a key technology for visualizing and detecting what was otherwise unseen in live cells. The target signaling included second messengers, protein phosphorylations, protein-protein interactions, and protein localizations.
引用
收藏
页码:304 / 312
页数:9
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