Outcomes for Cancer Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

被引:5
作者
Jacobs, Joshua A. [1 ]
Pickworth, Kerry [1 ]
Boudoulas, Konstantinos Dean [2 ]
Hinkley, Megan [3 ]
McLaughlin, Eric [4 ]
Blais, Danielle [1 ]
机构
[1] Ohio State Univ, Wexner Med Ctr, Richard M Ross Heart Hosp, Columbus, OH 43210 USA
[2] Ohio State Univ, Div Cardiovasc Med, Columbus, OH 43210 USA
[3] Ohio State Univ, Wexner Med Ctr, James Canc Hosp, Columbus, OH 43210 USA
[4] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA
关键词
STEMI; Cancer; Complications; HEART-DISEASE; RISK;
D O I
10.1016/j.carrev.2018.10.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Purpose: The incidence of cardiovascular disease in cancer patients is rising. The risk of in-hospital complications for cancer patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) is not well defined. Methods/Materials: A retrospective single-center cohort assessing STEM patients with a history of cancer (n = 58) and without a history of cancer (n = 551) who underwent primary PCI between January 1, 2012 and June 30, 2017 was conducted. The primary outcome was a composite of in-hospital complications including reinfarction, cardiogenic shock, new heart failure, stroke, new atrial fibrillation, ventricular tachycardia/fibrillation, cardiac arrest, bleeding, new dialysis requirement, mechanical circulatory support, hospice requirement, and in-hospital mortality. Results: Overall in-hospital complications occurred in 229 (37.6%) patients. There was no significant difference in overall complications in patients with a history of cancer (39.7%). compared to those without a cancer history (37.4%) (adjusted OR 0.84 [0.46-1.51], p = 0.58; unadjusted OR 1.10[0.61-1.92], p = 0.73); there were no differences exhibited in any of the individual complications. Patients with a history of cancer were significantly more likely to be readmitted within 30 days (12.7% vs. 5%; p = 0.03) and receive bare metal stents (50% vs. 30.4%; p = 0.004) as compared to patients without a history of cancer. Conclusions: There was no significant difference for in-hospital complications in patients with a history of cancer and those without a history of cancer undergoing primary PCI for STEMI. Patients with a history of cancer were more likely to readmitted within 30 days and receive bare metal stents. Summary: The risk of in-hospital complications for cancer patients with STEMI undergoing primary PCI is not well defined. In a single-center retrospective cohort, there was no significant difference for in-hospital complications between patients with a history of cancer and those without a history of cancer undergoing primary PCI for STEMI. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码:711 / 715
页数:5
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