Rapid biochemical assays for phenotypic drug resistance testing of HIV-1

被引:3
作者
García-Lerma, JG [1 ]
Heneine, W [1 ]
机构
[1] CDCP, HIV & Retrovirol Branch, Div AIDS STD & TB Lab Res, Atlanta, GA 30333 USA
关键词
HIV; drug resistance;
D O I
10.1093/jac/dkg005
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In summary, the need for rapid and simple drug resistance assays is becoming more critical as drug resistance testing is increasingly integrated into patient management. Such assays may also provide a rational approach for resistance testing in resource-poor settings where the use of antiretroviral drugs is expected to increase in the near future. © Oxford University Press 2001.
引用
收藏
页码:771 / 774
页数:4
相关论文
共 29 条
  • [21] HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    Perelson, AS
    Neumann, AU
    Markowitz, M
    Leonard, JM
    Ho, DD
    [J]. SCIENCE, 1996, 271 (5255) : 1582 - 1586
  • [22] A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1
    Petropoulos, CJ
    Parkin, NT
    Limoli, KL
    Lie, YS
    Wrin, T
    Huang, W
    Tian, H
    Smith, D
    Winslow, GA
    Capon, DJ
    Whitcomb, JM
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (04) : 920 - 928
  • [23] Comparative analysis of two commercial phenotypic assays for drug susceptibility testing of human immunodeficiency virus type 1
    Qari, SH
    Respess, R
    Weinstock, H
    Beltrami, EM
    Hertogs, K
    Larder, BA
    Petropoulos, CJ
    Hellmann, N
    Heneine, W
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (01) : 31 - 35
  • [24] Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies
    Race, E
    Dam, E
    Obry, V
    Paulous, S
    Clavel, F
    [J]. AIDS, 1999, 13 (15) : 2061 - 2068
  • [25] Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene
    Stuyver, L
    Wyseur, A
    Rombout, A
    Louwagie, J
    Scarcez, T
    Verhofstede, C
    Rimland, D
    Schinazi, RF
    Rossau, R
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (02) : 284 - 291
  • [26] *US DEP HHS HJ KAI, 2001, GUID US ANT AG HIV I
  • [27] Rapid screening of phenotypic resistance to nevirapine by direct analysis of HIV type 1 reverse transcriptase activity in plasma
    Vázquez-Rosales, G
    Lerma, JGG
    Yamamoto, S
    Switzer, WM
    Havlir, D
    Folks, TM
    Richman, DD
    Heneine, W
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1999, 15 (13) : 1191 - 1200
  • [28] Villahermosa ML, 2001, J HUMAN VIROL, V4, P238
  • [29] Highly sensitive qualitative and quantitative detection of reverse transcriptase activity: Optimization, validation, and comparative analysis with other detection systems
    Yamamoto, S
    Folks, TM
    Heneine, W
    [J]. JOURNAL OF VIROLOGICAL METHODS, 1996, 61 (1-2) : 135 - 143