The Role of Zinc in Cardiovascular Disease

被引：13
作者：
Begum, Farhana [1 ]
Me, Hay Me [2 ]
Christov, Marta [2 ]
机构：
[1] Zucker Sch Med Northwell NS LIJ, Dept Med, Manhasset, NY USA
[2] New York Med Coll, Westchester Med Ctr, Dept Med, Valhalla, NY USA
来源：
CARDIOLOGY IN REVIEW | 2022年 / 30卷 / 02期
关键词：
Zinc; cardiovascular; CKD/ESRD; diabetes mellitus; myocardial infarction; heart failure; vascular calcification; ACUTE MYOCARDIAL-INFARCTION; SERUM ZINC; OXIDATIVE STRESS; TRACE-ELEMENTS; PLASMA ZINC; RISK; INFLAMMATION; COPPER; SUPPLEMENTATION; HEMODIALYSIS;
D O I：
10.1097/CRD.0000000000000382
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Zinc is an essential trace element due to its role as a key part of human enzymatic activity. As a cofactor in metalloenzymes and metalloproteins, zinc participates in diverse biological functions, including gene transcription, translation, and replication, phagocytosis, and immunoglobulin and cytokine production. In this review, we will focus on the role of zinc in the cardiovascular system, including heart failure, vascular calcification, and myocardial infarction. We will further highlight the role of zinc in cardiovascular pathology in individuals with chronic kidney disease, and type II diabetes mellitus, groups uniquely at risk for cardiovascular morbidity and mortality.
引用
收藏
页码：100 / 108
页数：9
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