Infant milk-feeding practices and food allergies, allergic rhinitis, atopic dermatitis, and asthma throughout the life span: a systematic review

被引：85

作者：

Gungor, Darcy ^{[1
]}

Nadaud, Perrine ^{[1
]}

LaPergola, Concetta C. ^{[1
]}

Dreibelbis, Carol ^{[1
]}

Wong, Yat Ping ^{[2
]}

Terry, Nancy ^{[3
]}

Abrams, Steve A. ^{[4
]}

Beker, Leila ^{[5
]}

Jacobovits, Tova ^{[5
]}

Jarvinen, Kirsi M. ^{[6
]}

Nommsen-Rivers, Laurie A. ^{[7
]}

O'Brien, Kimberly O. ^{[8
]}

Oken, Emily ^{[9
,10
,11
]}

Perez-Escamilla, Rafael ^{[12
]}

Ziegler, Ekhard E. ^{[1
,13
]}

Spahn, Joanne M. ^{[2
]}

机构：

[1] Panum Grp, Bethesda, MD 20814 USA

[2] Food & Nutr Serv, USDA, Alexandria, VA USA

[3] Natl Inst Hlth Lib, Bethesda, MD USA

[4] Univ Texas Austin, Dell Med Sch, Austin, TX 78712 USA

[5] US FDA, College Pk, MD USA

[6] Univ Rochester, Med Ctr, Rochester, NY 14642 USA

[7] Univ Cincinnati, Coll Allied Hlth Sci, Cincinnati, OH USA

[8] Cornell Univ, Div Nutr Sci, Ithaca, NY 14853 USA

[9] Harvard Med Sch, Dept Populat Med, Div Chron Dis Res Lifecourse, Boston, MA 02115 USA

[10] Harvard Pilgrim Hlth Care Inst, Boston, MA USA

[11] Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA

[12] Yale Sch Publ Hlth, Dept Social & Behav Sci, New Haven, CT USA

[13] Univ Iowa, Dept Pediat, Iowa City, IA 52242 USA

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 2019年 / 109卷

关键词：

breastfeeding; humanmilk; food allergy; atopic dermatitis; allergic rhinitis; asthma; infant; toddler; child; systematic review; 1ST; 2; YEARS; RISK-FACTORS; CHILDHOOD ASTHMA; COMPLEMENTARY FOODS; PROSPECTIVE COHORT; INCIDENCE RATES; YOUNG-CHILDREN; EARLY EXPOSURE; BREAST-MILK; FOLLOW-UP;

D O I：

10.1093/ajcn/nqy283

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Background: During the Pregnancy and Birth to 24 Months Project, the USDA and Department of Health and Human Services initiated a review of evidence on diet and health in these populations. Objectives: The aim of these systematic reviews was to examine the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations of exclusive human milk feeding prior to infant formula introduction, 4) feeding a lower versus higher intensity of human milk to mixed-fed infants, and 5) feeding a higher intensity of human milk by bottle versus breast with food allergies, allergic rhinitis, atopic dermatitis, and asthma. Methods: The Nutrition Evidence Systematic Review team conducted systematic reviews with external experts. We searched CINAHL, Cochrane, Embase, and PubMed for articles published between January 1980 and March 2016, dual-screened the results according to predetermined criteria, extracted data from and assessed the risk of bias for each included study, qualitatively synthesized the evidence, developed conclusion statements, and graded the strength of the evidence. Results: The systematic reviews numbered 1-5 above included 44, 35, 1, 0, and 0 articles, respectively. Moderate, mostly observational, evidence suggests that 1) never versus ever being fed human milk is associated with higher risk of childhood asthma, and 2) among children and adolescents who were fed human milk as infants, shorter versus longer durations of any human milk feeding are associated with higher risk of asthma. Limited evidence does not suggest associations between 1) never versus ever being fed human milk and atopic dermatitis in childhood or 2) the duration of any human milk feeding and allergic rhinitis and atopic dermatitis in childhood. Conclusions: Moderate evidence suggests that feeding human milk for short durations or not at all is associated with higher childhood asthma risk. Evidence on food allergies, allergic rhinitis, and atopic dermatitis is limited.

引用

页码：772S / 799S

页数：28

共 88 条

[1] Asthma and sensitization in a community with low indoor allergen levels and low pet-keeping frequency [J].