Effect of 176Lu background on singles transmission for LSO-based PET cameras

被引：40
作者：
Huber, JS [1 ]
Moses, WW
Jones, WF
Watson, CC
机构：
[1] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
[2] CPS Innovat, Knoxville, TN 37932 USA
来源：
PHYSICS IN MEDICINE AND BIOLOGY | 2002年 / 47卷 / 19期
关键词：
D O I：
10.1088/0031-9155/47/19/307
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We explore how the radioactive background from naturally occurring Lu-176 affects single photon transmission imaging for lutetium orthosilicate (LSO) scintillator-based PET cameras by estimating the transmission noise equivalent count rate (NECR) including this background. Assuming a typical PET camera geometry (80 cm detector ring diameter), we use a combination of measurement and analytic computation to estimate the counting rates due to transmission, scatter and background events as a function of singles transmission source strength. We then compute a NECR for singles transmission. We find that the presence of radiation from the naturally occurring Lu-176 reduces the NECR by 60% or higher for source strengths less than 10 mCi, and that a 25% reduction of the NECR can occur even with a source strength of 40 mCi.
引用
收藏
页码：3535 / 3541
页数：7
相关论文
共 23 条
[1]  
BAILEY DL, 1997, P C IEEE NUCL SCI S, P1009
[2]  
Chatziioannou AF, 1999, J NUCL MED, V40, P1164
[3]   MicroPET: A high resolution PET scanner for imaging small animals [J].
Cherry, SR ;
Shao, Y ;
Silverman, RW ;
Meadors, K ;
Siegel, S ;
Chatziioannou, A ;
Young, JW ;
Jones, WF ;
Moyers, JC ;
Newport, D ;
Boutefnouchet, A ;
Farquhar, TH ;
Andreaco, M ;
Paulus, MJ ;
Binkley, DM ;
Nutt, R ;
Phelps, ME .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1997, 44 (03) :1161-1166
[4]   Development of a small animal PET imaging device with resolution approaching 1 mm [J].
Correia, JA ;
Burnham, CA ;
Kaufman, D ;
Fischman, AJ .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1999, 46 (03) :631-635
[5]   ATTENUATION CORRECTION IN PET USING SINGLE-PHOTON TRANSMISSION MEASUREMENT [J].
DEKEMP, RA ;
NAHMIAS, C .
MEDICAL PHYSICS, 1994, 21 (06) :771-778
[6]   A small animal PET prototype based on LSO crystals read out by avalanche photodiodes [J].
Fries, O ;
Bradbury, SM ;
Gebauer, J ;
Holl, I ;
Lorenz, E ;
Renker, D ;
Ziegler, SI .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 387 (1-2) :220-224
[7]   Conceptual design of a high-sensitivity small animal PET camera with 4π coverage [J].
Huber, JS ;
Moses, WW .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1999, 46 (03) :498-502
[8]   SINGLES TRANSMISSION IN VOLUME-IMAGING PET WITH A CS-137 SOURCE [J].
KARP, JS ;
MUEHLLEHNER, G ;
QU, H ;
YAN, XH .
PHYSICS IN MEDICINE AND BIOLOGY, 1995, 40 (05) :929-944
[9]  
KARP JS, 2000, P C IEEE NUCL SCI S
[10]   ADVANTAGES AND LIMITATIONS OF LSO SCINTILLATOR IN NUCLEAR-PHYSICS EXPERIMENTS [J].
LUDZIEJEWSKI, T ;
MOSZYNSKA, K ;
MOSZYNSKI, M ;
WOLSKI, D ;
KLAMRA, W ;
NORLIN, LO ;
DEVITSIN, E ;
KOZLOV, V .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1995, 42 (04) :328-336
123