Preliminary Results for the Inhibition of Pancreatic Cancer Cells by Organotin Polymers

被引：25
|
作者：
Roner, Michael R. [2 ]
Shahi, Kimberly R. [2 ]
Barot, Girish [1 ,3 ]
Battin, Amitabh [1 ,3 ]
Carraher, Charles E., Jr. [1 ,3 ]
机构：
[1] Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA
[2] Univ Texas Arlington, Dept Biol, Arlington, TX 76010 USA
[3] Florida Ctr Environm Studies, Palm Beach Gardens, FL 33410 USA
来源：
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2009年 / 19卷 / 03期
关键词：
Pancreatic cancer; Organotin polymers; Pancreatic cancer chemotherapy; Organotin polyethers; Soluble organotin polyethers; Organotin polyamines; STRUCTURAL-CHARACTERIZATION; PRELIMINARY ANTICANCER; TITANOCENE DICHLORIDE; DIETHYLSTILBESTROL; DERIVATIVES; POLYETHERS; DRUGS;
D O I：
10.1007/s10904-009-9275-7
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Pancreatic cancer kills nearly all patients within 3-6 months after detection. There is no effective chemotherapy for it. We have found a number of organotin polymers that are effective at inhibiting pancreatic cancer cell lines with Chemotherapeutic Index values greater than two with some to values of 50.
引用
收藏
页码：410 / 414
页数：5
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