Preliminary Results for the Inhibition of Pancreatic Cancer Cells by Organotin Polymers

被引：25
|
作者：
Roner, Michael R. [2 ]
Shahi, Kimberly R. [2 ]
Barot, Girish [1 ,3 ]
Battin, Amitabh [1 ,3 ]
Carraher, Charles E., Jr. [1 ,3 ]
机构：
[1] Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA
[2] Univ Texas Arlington, Dept Biol, Arlington, TX 76010 USA
[3] Florida Ctr Environm Studies, Palm Beach Gardens, FL 33410 USA
来源：
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2009年 / 19卷 / 03期
关键词：
Pancreatic cancer; Organotin polymers; Pancreatic cancer chemotherapy; Organotin polyethers; Soluble organotin polyethers; Organotin polyamines; STRUCTURAL-CHARACTERIZATION; PRELIMINARY ANTICANCER; TITANOCENE DICHLORIDE; DIETHYLSTILBESTROL; DERIVATIVES; POLYETHERS; DRUGS;
D O I：
10.1007/s10904-009-9275-7
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Pancreatic cancer kills nearly all patients within 3-6 months after detection. There is no effective chemotherapy for it. We have found a number of organotin polymers that are effective at inhibiting pancreatic cancer cell lines with Chemotherapeutic Index values greater than two with some to values of 50.
引用
收藏
页码：410 / 414
页数：5
相关论文
共 50 条
  • [1] Preliminary Results for the Inhibition of Pancreatic Cancer Cells by Organotin Polymers
    Michael R. Roner
    Kimberly R. Shahi
    Girish Barot
    Amitabh Battin
    Charles E. Carraher
    Journal of Inorganic and Organometallic Polymers and Materials, 2009, 19 : 410 - 414
  • [2] Inhibition of pancreatic cancer cell lines by selected organotin polymers
    Shahi, Kimberly R.
    Roner, Michael R.
    Barot, Girish
    Battin, Amitabh J.
    Carraher, Charles E., Jr.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [3] Synthesis and Preliminary Anticancer Results for Polymers From the Reaction of Organotin Dihalides and Thiodiglycolic Acid
    Carraher, Charles E., Jr.
    Roner, Michael R.
    Pham, Ngoc
    Miller, Lindsey C.
    Black, Kendra
    Crichton, Ryan
    JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2015, 52 (10): : 786 - 797
  • [4] Ability of organotin polymers derived from thiamine to inhibit ovarian, colon, lung, prostrate, pancreatic and breast cancer cells
    Roner, Michael R.
    Lambert, Raven E.
    Carraher, Charles E., Jr.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [5] Laparoscopic palliation of pancreatic cancer:: preliminary results
    Röthlin, M
    Schöb, O
    SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT, 1999, 129 (19) : 731 - 735
  • [6] Organotin Polymers As Chemotherapeutic Agents: Breast and Pancreatic Cancers
    Carraher, Charles E., Jr.
    Roner, Michael R.
    Shahi, Kimberly
    Battin, Amitabh
    Barot, Girish
    Arnold, Tiasha
    JOURNAL OF POLYMER MATERIALS, 2014, 31 (01): : 1 - 14
  • [7] Growth inhibition of Balb 3T3 cells by organotin pyrimidine polymers
    Siegmann-Louda, DW
    Carraher, CE
    Gordon, O
    Battin, AJ
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U3622 - U3622
  • [8] Electrochemotherapy in locally advanced pancreatic cancer: Preliminary results
    Granata, V.
    Fusco, R.
    Piccirillo, M.
    Palaia, R.
    Petrillo, A.
    Lastoria, S.
    Izzo, F.
    INTERNATIONAL JOURNAL OF SURGERY, 2015, 18 : 230 - 236
  • [9] Control of Prostate Cancer Using Organotin Polymers
    Carraher, Charles E., Jr.
    Roner, Michael R.
    Shahi, Kimberly
    Moric-Johnson, Alisa
    Miller, Lindsey
    Barot, Girish
    Battin, Amitabh
    Trang, Nancy T.
    Al-Huniti, Mohammed H.
    JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2015, 25 (03) : 386 - 399
  • [10] Control of Breast Cancer Using Organotin Polymers
    Carraher, Charles E., Jr.
    Roner, Michael R.
    Shahi, Kimberly
    Moric-Johnson, Alisa
    Miller, Lindsey
    Barot, Girish
    Battin, Amitabh
    Trang, Nancy T.
    Sookdeo, Nandalall
    Islam, Zamil
    INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2015, 64 (15) : 800 - 814
12345