Sex-biased Immune Responses Following SARS-CoV-2 Infection

被引:11
|
作者
Ursin, Rebecca L. [1 ]
Shapiro, Janna R. [2 ]
Klein, Sabra L. [1 ,2 ,3 ]
机构
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Biochem & Mol Biol, Baltimore, MD 21205 USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA
[3] Johns Hopkins Bloomberg Sch Publ Hlth, W Harry Feinstone Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA
关键词
D O I
10.1016/j.tim.2020.10.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).
引用
收藏
页码:952 / 954
页数:3
相关论文
共 50 条
  • [21] Foetal sex affects maternal and placental immune responses to SARS-CoV-2
    Flemming A.
    Nature Reviews Immunology, 2021, 21 (12) : 761 - 761
  • [22] Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS-CoV-2 Omicron infection
    Toh, Zheng Quan
    Anderson, Jeremy
    Mazarakis, Nadia
    Quah, Leanne
    Nguyen, Jill
    Higgins, Rachel A.
    Do, Lien Anh Ha
    Ng, Yan Yung
    Jalali, Sedi
    Neeland, Melanie R.
    McMinn, Alissa
    Saffery, Richard
    McNab, Sarah
    McVernon, Jodie
    Marcato, Adrian
    Burgner, David P.
    Curtis, Nigel
    Steer, Andrew C.
    Mulholland, Kim
    Pellicci, Daniel G.
    Crawford, Nigel W.
    Tosif, Shidan
    Licciardi, Paul, V
    CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2024, 13 (10)
  • [23] Hematopoietic responses to SARS-CoV-2 infection
    Elahi, Shokrollah
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2022, 79 (03)
  • [24] Hematopoietic responses to SARS-CoV-2 infection
    Shokrollah Elahi
    Cellular and Molecular Life Sciences, 2022, 79
  • [25] Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose
    Bladh, Oscar
    Marking, Ulrika
    Havervall, Sebastian
    Norin, Nina Greilert
    Aguilera, Katherina
    Hober, Sophia
    Smed-Soerensen, Anna
    Gordon, Max
    Blom, Kim
    Aberg, Mikael
    Klingstrom, Jonas
    Thalin, Charlotte
    LANCET MICROBE, 2023, 4 (07): : E488 - E488
  • [26] SARS-CoV-2 infection in children - Understanding the immune responses and controlling the pandemic
    Lu, Xiaoxia
    Xiang, Yun
    Du, Hui
    Wing-Kin Wong, Gary
    PEDIATRIC ALLERGY AND IMMUNOLOGY, 2020, 31 (05) : 449 - 453
  • [27] Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults
    Kared, Hassen
    Wolf, Asia-Sophia
    Alirezaylavasani, Amin
    Ravussin, Anthony
    Solum, Guri
    Tran, Trung The
    Lund-Johansen, Fridtjof
    Vaage, John Torgils
    Nissen-Meyer, Lise Sofie
    Nygaard, Unni C.
    Hungnes, Olav
    Robertson, Anna H.
    Naess, Lisbeth Meyer
    Trogstad, Lill
    Magnus, Per
    Munthe, Ludvig A.
    Mjaaland, Siri
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [28] Mechanistic understanding of innate and adaptive immune responses in SARS-CoV-2 infection
    Balkhi, Mumtaz Y.
    MOLECULAR IMMUNOLOGY, 2021, 135 : 268 - 275
  • [29] Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults
    Hassen Kared
    Asia-Sophia Wolf
    Amin Alirezaylavasani
    Anthony Ravussin
    Guri Solum
    Trung The Tran
    Fridtjof Lund-Johansen
    John Torgils Vaage
    Lise Sofie Nissen-Meyer
    Unni C. Nygaard
    Olav Hungnes
    Anna H. Robertson
    Lisbeth Meyer Næss
    Lill Trogstad
    Per Magnus
    Ludvig A. Munthe
    Siri Mjaaland
    Nature Communications, 13
  • [30] Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
    Pierce, Carl A.
    Preston-Hurlburt, Paula
    Dai, Yile
    Aschner, Clare Burn
    Cheshenko, Natalia
    Galen, Benjamin
    Garforth, Scott J.
    Herrera, Natalia G.
    Jangra, Rohit K.
    Morano, Nicholas C.
    Orner, Erika
    Sy, Sharlene
    Chandran, Kartik
    Dziura, James
    Almo, Steven C.
    Ring, Aaron
    Keller, Marla J.
    Herold, Kevan C.
    Herold, Betsy C.
    SCIENCE TRANSLATIONAL MEDICINE, 2020, 12 (564)