Biological consequences of zinc deficiency in the pathomechanisms of selected diseases

被引:125
作者
Jurowski, Kamil [1 ,2 ]
Szewczyk, Bernadeta [3 ]
Nowak, Gabriel [3 ,4 ]
Piekoszewski, Wojciech [1 ,5 ]
机构
[1] Jagiellonian Univ, Fac Chem, Dept Analyt Chem, PL-30060 Krakow, Poland
[2] Jagiellonian Univ, Coll Med, Fac Med, Malopolska Ctr Translat Med, PL-30060 Krakow, Poland
[3] Polish Acad Sci, Inst Pharmacol, Krakow, Poland
[4] Jagiellonian Univ, Coll Med, Fac Pharm, PL-30060 Krakow, Poland
[5] Jagiellonian Univ, Lab High Resolut Mass Spectrometry, Reg Lab Physicochem Anal & Struct Res, Fac Chem, PL-30060 Krakow, Poland
来源
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 2014年 / 19卷 / 07期
关键词
Zinc deficiency; Zinc diseases; Zinc pathomechanisms; ALZHEIMERS-DISEASE; DEPRESSIVE SYMPTOMS; DIABETES-MELLITUS; WILSON-DISEASE; TRACE-ELEMENTS; BLOOD-PRESSURE; INSULIN; SUPPLEMENTATION; COPPER; MICE;
D O I
10.1007/s00775-014-1139-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected diseases such as depression, cardiovascular diseases, diabetes mellitus, Alzheimer's disease, and Wilson's disease.
引用
收藏
页码:1069 / 1079
页数:11
相关论文
共 137 条
[1]   Zinc Mono-Therapy in Pre-Symptomatic Chinese Children with Wilson Disease: A Single Center, Retrospective Study [J].
Abuduxikuer, Kuerbanjiang ;
Wang, Jian-She .
PLOS ONE, 2014, 9 (01)
[2]   Cognitive Loss in Zinc Transporter-3 Knock-Out Mice: A Phenocopy for the Synaptic and Memory Deficits of Alzheimer's Disease? [J].
Adlard, Paul A. ;
Parncutt, Jacqui M. ;
Finkelstein, David I. ;
Bush, Ashley I. .
JOURNAL OF NEUROSCIENCE, 2010, 30 (05) :1631-1636
[3]  
Alzheimer A., 1907, Allg Zeitschrift Psychiatr, V64, P146, DOI DOI 10.1002/CA.980080612
[4]   Correlation Between Dietary Zinc Intakes and Its Serum Levels with Depression Scales in Young Female Students [J].
Amani, Reza ;
Saeidi, Somaye ;
Nazari, Zahra ;
Nematpour, Sorour .
BIOLOGICAL TRACE ELEMENT RESEARCH, 2010, 137 (02) :150-158
[5]  
[Anonymous], 1997, INT J DIABETES DEV C
[6]  
ATLIHAN F, 1990, TURKISH J PEDIATR, V32, P33
[7]   Physicochemical basis for the rapid time-action of Lys(B28)Pro(B29)-insulin: Dissociation of a protein-ligand complex [J].
Bakaysa, DL ;
Radziuk, J ;
Havel, HA ;
Brader, ML ;
Li, S ;
Dodd, SW ;
Beals, JM ;
Pekar, AH ;
Brems, DN .
PROTEIN SCIENCE, 1996, 5 (12) :2521-2531
[8]   Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent [J].
Bao, Bin ;
Prasad, Ananda S. ;
Beck, Frances W. J. ;
Fitzgerald, James T. ;
Snell, Diane ;
Bao, Ginny W. ;
Singh, Tapinder ;
Cardozo, Lavoisier J. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 91 (06) :1634-1641
[9]   Zinc [J].
Barceloux, DG .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1999, 37 (02) :279-292
[10]  
Bardsley Joan K, 2004, Crit Care Nurs Q, V27, P106